Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Panda, Horse (94%) Rat, Bovine, Elephant (88%) Mouse, Dog (81%).
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT-5; 5-HT-5A; 5-HT5a receptor; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; 5-hydroxytryptamine receptor 5A; 5-hydroxytryptamine5a; 5HT5A; Serotonin receptor 5A
Gene Aliases: 5-HT5A; HTR5A
UniProt ID: (Human) Q2M2D2
Entrez Gene ID: (Human) 3361
Molecular Function: G-protein coupled receptor