Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%).
Hormonally upregulated Neu tumor-associated kinase (HUNK), an AMPK/SNF1-type protein kinase, contains a domain homologous to SNF1, a protein involved in the response to nutritional stress in yeast. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
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Protein Aliases: B19; Hormonally up-regulated neu tumor-associated kinase; hormonally upregulated neu tumor-associated kinase; hormonally upregulated Neu-associated kinase; serine/threonine protein kinase MAK-V; Serine/threonine-protein kinase MAK-V
Gene Aliases: HUNK; MAKV
UniProt ID: (Human) P57058
Entrez Gene ID: (Human) 30811