Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hyal-1; Hyaluronidase-1; Hyaluronoglucosaminidase-1; LuCa-1; Lung carcinoma protein 1; plasma hyaluronidase; tumor suppressor LUCA-1
Gene Aliases: HYAL-1; HYAL1; LUCA1; MPS9; NAT6
UniProt ID: (Human) Q12794
Entrez Gene ID: (Human) 3373
Molecular Function:
glycosidase
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