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Hairless Polyclonal Antibody
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Product Details
BS-8507R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Hairless
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Drosophila genes can be categorized based on the type of protein for which they encode and are represented by six major classifications, which include intracellular signaling proteins, transmembrane proteins, RNA binding proteins, secreted factors, transcription regulators (basic helix-loop-helix, homeodomain containing, zinc finger containing and chromatin associated) or other functional proteins. Among these numerous proteins, Hairless (CG5460, CT36411, CT17282) is a transcriptional co-repressor that contains a "Paired box" domain, a KX-repeat domain, a NEDL-repeat domain and a serine-rich domain. Hairless is an antagonist of the Notch signaling pathway in Drosophila.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-dimethyl-L-lysine(9) demethylase hairless; HAIR; hair growth associated; hairless homolog; Hairless protein; Lysine-specific demethylase hairless; protein hairless; restricted expression in the brain and skin
Gene Aliases: ALUNC; AU; ba; bldy; HR; HSA277165; HYPT4; MUHH; MUHH1; N; rh; rh-bmh; rhino
UniProt ID: (Human) O43593, (Mouse) Q61645
Entrez Gene ID: (Human) 55806, (Mouse) 15460, (Rat) 60563
DNA binding
transcription cofactor activity
transcription corepressor activity
protein binding
zinc ion binding
oxidoreductase activity
chromatin DNA binding
histone demethylase activity (H3-K9 specific)
metal ion binding
histone H3K9me/H3K9me2 demethylase activity
sulfonate dioxygenase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
vitamin D receptor binding
histone deacetylase binding
DNA-N1-methyladenine dioxygenase activity
thyroid hormone receptor binding
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone modifying enzyme
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
oxidation-reduction process
negative regulation of nucleic acid-templated transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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