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Invitrogen
Hairless Polyclonal Antibody
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Product Details
PA5-37443
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 51-100 of human Hairless
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 127 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Drosophila genes can be categorized based on the type of protein for which they encode and are represented by six major classifications, which include intracellular signaling proteins, transmembrane proteins, RNA binding proteins, secreted factors, transcription regulators (basic helix-loop-helix, homeodomain containing, zinc finger containing and chromatin associated) or other functional proteins. Among these numerous proteins, Hairless (CG5460, CT36411, CT17282) is a transcriptional co-repressor that contains a "Paired box" domain, a KX-repeat domain, a NEDL-repeat domain and a serine-rich domain. Hairless is an antagonist of the Notch signaling pathway in Drosophila.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-dimethyl-L-lysine(9) demethylase hairless; HAIR; hairless homolog; Hairless protein; Lysine-specific demethylase hairless; protein hairless
Gene Aliases: ALUNC; AU; ba; bldy; HR; HSA277165; HYPT4; MUHH; MUHH1; N; rh; rh-bmh; rhino
UniProt ID: (Human) O43593, (Mouse) Q61645
Entrez Gene ID: (Human) 55806, (Mouse) 15460, (Rat) 60563
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
oxidoreductase activity
vitamin D receptor binding
histone deacetylase binding
metal ion binding
thyroid hormone receptor binding
sulfonate dioxygenase activity
protein binding
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone modifying enzyme
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
protein heterooligomerization
oxidation-reduction process
negative regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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