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          • Primary Antibodies ›
          • Hemoglobin alpha Antibodies

          Proteintech

          Hemoglobin Alpha Polyclonal Antibody, CoraLite® 594

          View all (7) Hemoglobin alpha antibodies

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          Cite Hemoglobin Alpha Polyclonal Antibody, CoraLite® 594

          • Antibody Testing Data (2)
          Hemoglobin Alpha Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
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          Hemoglobin Alpha Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
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          FIGURE: 1 / 2

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          Hemoglobin Alpha Antibody (CL594-14537) in IHC (PFA)

          Immunofluorescent analysis of (4% PFA) fixed human appendicitis tissue using CoraLite®594 Hemoglobin Alpha antibody (CL594-14537) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Hemoglobin Alpha Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Hemoglobin Alpha Antibody in Flow Cytometry (Flow)

          Product Details

          CL594-14537

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:200
          -

          Flow Cytometry (Flow)

          0.40 µg/10^6 cells in a 100 µL suspension
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Hemoglobin Alpha fusion protein Ag6040

          Conjugate

          CoraLite® 594 CoraLite® 594 CoraLite® 594

          Excitation/Emission Max

          593/614 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: MVLSPADKT NVKAAWGKVG AHAGEYGAEA LERMFLSFPT TKTYFPHFDL SHGSAQVKGH GKKVADALTN AVAHVDDMPN ALSALSDLHA HKLRVDPVNF KLLSHCLLVT LAAHLPAEFT PAVHASLDKF LASVSTVLTS KYR

          Target Information

          The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alpha 1 globin; alpha globin 1; alpha one globin; Alpha-1/2-globin; alpha-2 globin chain; Alpha-globin; delta globin; globin, alpha; haemaglobin alpha 1; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; Hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; Hemoglobin subunit alpha-1/2; hemoglobin, alpha 1

          View more View less

          Gene Aliases: GloA; Hba; Hba-a1; Hba-a2; HBA-T3; HBA1; HBA2; HBAM; Hbat1; HBH

          View more View less

          UniProt ID: (Human) P69905, (Rat) P01946

          View more View less

          Entrez Gene ID: (Human) 3039, (Mouse) 15122, (Rat) 25632, (Rat) 287167

          View more View less

          Function(s)
          peroxidase activity oxygen transporter activity iron ion binding protein binding oxygen binding heme binding haptoglobin binding beta-amyloid binding organic acid binding
          Process(es)
          in utero embryonic development erythrocyte development positive regulation of cell death oxygen transport response to hydrogen peroxide hydrogen peroxide catabolic process protein heterooligomerization oxidation-reduction process receptor-mediated endocytosis bicarbonate transport cellular oxidant detoxification negative regulation of blood pressure regulation of sensory perception of pain
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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