Immunogen sequence: TPLPPTSAHG NVAEGETKPD PDVTERCSDG WSFDATTLDD NGTMLFFKGE FVWKSHKWDR ELISERWKNF PSPVDAAFRQ GHNSVFLIKG DKVWVYPPEK KEKGYPKLLQ DEFPGIPSPL DAAVECHRGE CQAEGVLFFQ GDREWFWDLA TGTMKERSWP AVGNCSSALR WLGRYYCFQG NQFLRFDPVR GEVPPRYPRD VRDYFMPCPG RGHGHRNGTG HG; Positive Samples: HL-60, HepG2, BT-474, Mouse liver, Mouse pancreas
Hemopexin is a serum glycoprotein that binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Structurally, hemopexin consists of two similar halves of approximately two hundred amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues.
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Protein Aliases: Beta-1B-glycoprotein; Hemopexin
Gene Aliases: HPX; Hpxn; HX
Molecular Function: transfer/carrier protein