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Hepsin Antibody (PA5-97839) in ICC/IF
Immunofluorescent analysis of Hepsin in MCF-7 cells using a Hepsin polyclonal antibody (Product # PA5-97839) at a dilution of 1:133. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were counter-stained with DAPI.
Product Details
PA5-97839
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Serine protease hepsin protein (294-413AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2812453
Target Information
Hepsin is a cell surface serine protease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hepsin (transmembrane protease, serine 1); Serine protease hepsin; testicular tissue protein Li 85; Transmembrane protease serine 1
Gene Aliases: Hlb320; HPN; TMPRSS1
UniProt ID: (Human) P05981, (Rat) Q05511, (Mouse) O35453
Entrez Gene ID: (Human) 3249, (Rat) 29135, (Mouse) 15451
proteolysis
regulation of cell shape
positive regulation of gene expression
negative regulation of epithelial to mesenchymal transition
positive regulation of plasminogen activation
positive regulation of cell growth
basement membrane disassembly
negative regulation of apoptotic process
positive regulation by host of viral transcription
hepatocyte growth factor receptor signaling pathway
negative regulation of epithelial cell proliferation
detection of mechanical stimulus involved in sensory perception of sound
potassium ion transmembrane transport
cochlea morphogenesis
response to thyroid hormone
pilomotor reflex
positive regulation of hepatocyte proliferation
positive regulation of thyroid hormone generation
sensory perception of sound
negative regulation of alkaline phosphatase activity
cholesterol homeostasis
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