Proteintech

Histone H1.0 Polyclonal Antibody

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Histone H1.0 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HepG2 cells using 17510-1-AP (Histone H1.0 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IGG.

Histone H1.0 Antibody in Western Blot (WB) — Mouse spleen tissue were subjected to SDS PAGE followed by western blot with 17510-1-AP (Histone H1.0 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Histone H1.0 Antibody in Immunoprecipitation (IP) — IP result of anti-Histone H1.0 (IP:17510-1-AP, 4ug; Detection:17510-1-AP 1:500) with A431 cells lysate 2400ug.

Product Details

17510-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 11 publications 11 publications

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Histone H1.0 Fusion Protein Ag9982 (1-194 aa encoded by BC000145)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: MTENSTSAP AAKPKRAKAS KKSTDHPKYS DMIVAAIQAE KNRAGSSRQS IQKYIKSHYK VGENADSQIK LSIKRLVTTG VLKQTKGVGA SGSFRLAKSD EPKKSVAFKK TKKEIKKVAT PKKASKPKKA ASKAPTKKPK ATPVKKAKKK LAATPKKAKK PKTVKAKPVK ASKPKKAKPV KPKAKSSAKR AGKKK (1-194 aa encoded by BC000145)

Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.

Oncogene

Zheng X,Liu Z,Zhong J,Zhou L,Chen J,Zheng L,Li Z,Zhang R,Pan J,Wu Y,Liu Z,Kang T

Fri Jul 01 00:00:00 EDT 2022

Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.

Oncogene

Zheng X,Liu Z,Zhong J,Zhou L,Chen J,Zheng L,Li Z,Zhang R,Pan J,Wu Y,Liu Z,Kang T

Fri Jul 01 00:00:00 EDT 2022

RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.

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Wed Oct 27 00:00:00 EDT 2021

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Mon Sep 06 00:00:00 EDT 2021

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Jiang W,Chen C,Huang L,Shen J,Yang L

Tue May 18 00:00:00 EDT 2021

Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.

Journal of Cancer

Tian N,Shangguan W,Zhou Z,Yao Y,Fan C,Cai L

Thu Oct 01 00:00:00 EDT 2020

PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy.

Theranostics

Zeng J,Liu W,Fan YZ,He DL,Li L

Mon Nov 19 00:00:00 EST 2018

PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy.

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Zeng J,Liu W,Fan YZ,He DL,Li L

Mon Nov 19 00:00:00 EST 2018

Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.

Acta biochimica et biophysica Sinica

Liu H,Liu Q,Hua L,Pan J

Tue May 01 00:00:00 EDT 2018

Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.

Acta biochimica et biophysica Sinica

Liu H,Liu Q,Hua L,Pan J

Tue May 01 00:00:00 EDT 2018

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.

PLoS pathogens

Feng L,Sheng J,Vu GP,Liu Y,Foo C,Wu S,Trang P,Paliza-Carre M,Ran Y,Yang X,Sun X,Deng Z,Zhou T,Lu S,Li H,Liu F

Mon Jan 01 00:00:00 EST 2018

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.

PLoS pathogens

Feng L,Sheng J,Vu GP,Liu Y,Foo C,Wu S,Trang P,Paliza-Carre M,Ran Y,Yang X,Sun X,Deng Z,Zhou T,Lu S,Li H,Liu F

Mon Jan 01 00:00:00 EST 2018

ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.

Journal of physiology and biochemistry

Ren K,Lu YJ,Mo ZC,-Liu X,Tang ZL,Jiang Y,Peng XS,Li L,Zhang QH,Yi GH

Mon May 01 00:00:00 EDT 2017

ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.

Journal of physiology and biochemistry

Ren K,Lu YJ,Mo ZC,-Liu X,Tang ZL,Jiang Y,Peng XS,Li L,Zhang QH,Yi GH

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Tao M,Liu L,Shen M,Zhi Q,Gong FR,Zhou BP,Wu Y,Liu H,Chen K,Shen B,Wu MY,Shou LM,Li W

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Cell cycle (Georgetown, Tex.)

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Pin1 promotes GR transactivation by enhancing recruitment to target genes.

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Pin1 promotes GR transactivation by enhancing recruitment to target genes.

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Bioinformatics

Protein Aliases: H1 histone family, member 0; H1-0 histone; H1.0, H1(0), H1-0; Histone H1'; Histone H1(0); Histone H1-0; Histone H1.0; Histone H1.0, N-terminally processed; MyD196

Gene Aliases: D130017D06Rik; H1(0); H1-0; H10; H1F0; H1FV

UniProt ID: (Human) P07305, (Mouse) P10922, (Rat) P43278

Entrez Gene ID: (Human) 3005, (Mouse) 14958, (Rat) 24437

Molecular Function: histone