Search
AbboMax
Histone H2A Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
Histone H2A Antibody (630-200ABBOMAX) in WB
Western Blot: The nuclear extract derived from 3T3 cell lysate was resolved onto 12% SDS-PAGE, transferred onto NC membrane, and immunoprobed by Rabbit anti-Histone H2A antibody (Cat#630-200) at 1:500. An immunoreactive band is observed around ~15 kDa (Lane 1). The BSA (lane 2) was loaded as negative control.
Product Details
630-200ABBOMAX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide derived from C-term of Histone H2A protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: 3T3 Nuclear Extract
Cellular location: Nuclear.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2A 615 antibody; H2A GL101 antibody; H2A histone; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member R; H2A histone family, member X; H2A histone family, member Z; H2A-clustered histone 1; H2A-clustered histone 12; H2A.1; H2A.1 antibody; H2A.1b; H2A/d; H2a/x; H2A/z; h2ad; H2ae; H2AFX; H2AFZ; h2ai; H2ak; H2AK5ac; H2AX histone; H2AZ histone; H2B histone family, member U, (testis-specific); HIS; HIST1H2AE antibody; HIST1H3D; HIST3H2A; histone (H2A.Z); histone 1, H2aa; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1 H2A family member a; histone cluster 1 H2A family member b; histone cluster 1 H2A family member d; histone cluster 1 H2A family member e; histone cluster 1 H2A family member g; histone cluster 1 H2A family member h; histone cluster 1 H2A family member i; histone cluster 1 H2A family member j; histone cluster 1 H2B family member a; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2ba; histone H2A; Histone H2A type 1; Histone H2A type 1-A; Histone H2A type 1-B; Histone H2A type 1-B/E; Histone H2A type 1-D; Histone H2A type 1-E; Histone H2A type 1-G; Histone H2A type 1-H; Histone H2A type 1-I; Histone H2A type 1-J; Histone H2A type 4; Histone H2A, testis; histone H2A-III; Histone H2A-IV; Histone H2A.2; Histone H2A.3; Histone H2A.X; Histone H2A.Z; Histone H2A/a; Histone H2A/e; Histone H2A/g; Histone H2A/m; histone H2A/p; Histone H2A/ptl; Histone H2A/r; Histone H2A/s; histone H2AD; histone H2AE; Histone H2AX; Histone H2B type 1-A; Histone H2B, testis; MGC74460 antibody; similar to Histone H2A type 1; testis-specific histone 2a; testis-specific histone 2b; Testis-specific histone H2B; TH2A; TSH2B.1; unnamed protein product
Gene Aliases: 1190022L06; AW228881; bA317E16.2; bA317E16.3; dJ160A22.4; dJ86C11.1; gammaH2ax; H2a-291A; H2a-53; H2A-III; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.X; H2A.Z; H2A.Z-1; H2A/a; H2A/c; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2A/X; H2A/z; H2AA; H2AC1; H2AC11; H2AC12; H2AC13; H2AC14; H2AC15; H2AC16; H2AC17; H2AC4; H2AC7; H2AC8; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2AFR; H2AFX; H2AFZ; H2AG; H2AH; H2AX; H2AZ; H2AZ1; H2BC1; H2BFU; HIST1H2AA; HIST1H2AB; HIST1H2AD; HIST1H2AE; HIST1H2AG; HIST1H2AH; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; HIST1H2BA; Hist5-2ax; HISTH2AA; hTSH2B; pH2A/f; RGD1566119; STBP; TH2A; TH2B; TSH2B; TSH2B.1
UniProt ID: (Human) Q96QV6, (Human) P0C0S8, (Human) Q96KK5, (Human) Q99878, (Bovine) P0C0S9, (Human) P04908, (Human) P20671, (Human) P16104, (Bovine) P0C0S4, (Human) P0C0S5, (Human) Q96A08, (Mouse) P27661, (Mouse) P0C0S6, (Rat) P0C0S7, (Chicken) P02263, (Rat) Q00728, (Mouse) C0HKE1, (Mouse) C0HKE3, (Mouse) C0HKE4, (Mouse) C0HKE5, (Mouse) Q8CGP6, (Mouse) C0HKE6, (Rat) Q00729
Entrez Gene ID: (Human) 221613, (Human) 8969, (Human) 85235, (Human) 8329, (Human) 8331, (Bovine) 616790, (Human) 8335, (Human) 3013, (Human) 3012, (Chicken) 100857391, (Bovine) 531733, (Human) 3014, (Bovine) 287016, (Human) 3015, (Human) 255626, (Rat) 500987, (Mouse) 15270, (Mouse) 51788, (Rat) 58940, (Chicken) 427881, (Rat) 24828, (Mouse) 319172, (Mouse) 319165, (Mouse) 319166, (Mouse) 319167, (Mouse) 319168, (Mouse) 319191, (Rat) 24829, (Rat) 680322
DNA binding
structural constituent of chromatin
protein heterodimerization activity
protein binding
enzyme binding
damaged DNA binding
histone binding
chromatin-protein adaptor activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
chromatin DNA binding
nucleosomal DNA binding
molecular_function
RNA polymerase II distal enhancer sequence-specific DNA binding
histone
chromatin organization
heterochromatin assembly
negative regulation of cell proliferation
protein localization to CENP-A containing chromatin
DNA damage checkpoint
double-strand break repair via homologous recombination
DNA repair
double-strand break repair
DNA recombination
nucleosome assembly
cellular response to DNA damage stimulus
spermatogenesis
response to ionizing radiation
positive regulation of DNA repair
meiotic cell cycle
protein K63-linked ubiquitination
positive regulation of double-strand break repair via homologous recombination
protein localization to site of double-strand break
positive regulation of transcription from RNA polymerase II promoter
cellular response to estradiol stimulus
nucleosome disassembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
cerebral cortex development
cellular response to gamma radiation
cellular senescence
cell cycle
multicellular organism development
cellular response to insulin stimulus
chromatin silencing
biological_process
spermatogenesis, exchange of chromosomal proteins
positive regulation of binding
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support