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Histone H2A, acidic patch Polyclonal Antibody
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FIGURE: 1 / 2
Histone H2A, acidic patch Antibody (39111) in WB
Histone H2A, acidic patch pAb tested by Western blot. Detection of Histone H2A by Western blot. The analysis was performed using recombinant histone H2A protein (200 ng, lane 1) and acid extract of HeLa cells (5 µg, lane 2) probed with Histone H2A, acidic patch pAb (1:1,000 dilution).
Product Details
39111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This Histone H2A, acidic patch antibody was raised against a peptide including amino acids 89-91 of histone H2A.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum with 30% glycerol
Contains
0.035% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2A 615 antibody; H2A GL101 antibody; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member R; H2A-clustered histone 1; H2A-clustered histone 12; H2A.1; H2A.1 antibody; H2A/d; H2a/x; H2A/z; h2ad; H2ae; H2AFX; H2AFZ; h2ai; H2ak; H2AK5ac; H2AX histone; H2AZ histone; H2B histone family, member U, (testis-specific); HIS; HIST1H2AE antibody; HIST1H3D; HIST3H2A; histone (H2A.Z); histone 1, H2aa; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone cluster 1 H2A family member a; histone cluster 1 H2A family member b; histone cluster 1 H2A family member d; histone cluster 1 H2A family member e; histone cluster 1 H2A family member g; histone cluster 1 H2A family member h; histone cluster 1 H2A family member i; histone cluster 1 H2A family member j; histone cluster 1 H2B family member a; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2ba; Histone H2A type 1; Histone H2A type 1-A; Histone H2A type 1-B/E; Histone H2A type 1-D; Histone H2A type 1-H; Histone H2A type 1-J; Histone H2A.2; Histone H2A.3; Histone H2A.X; Histone H2A.Z; Histone H2A/a; Histone H2A/e; Histone H2A/g; Histone H2A/m; histone H2A/p; Histone H2A/ptl; Histone H2A/r; Histone H2A/s; histone H2AD; histone H2AE; Histone H2AX; Histone H2B type 1-A; Histone H2B, testis; MGC74460 antibody; Testis-specific histone H2B; TSH2B.1; unnamed protein product
Gene Aliases: bA317E16.2; bA317E16.3; dJ160A22.4; dJ86C11.1; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.X; H2A.z; H2A.Z-1; H2A/a; H2A/c; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2A/X; H2A/z; H2AA; H2AC1; H2AC11; H2AC12; H2AC13; H2AC14; H2AC15; H2AC16; H2AC17; H2AC4; H2AC7; H2AC8; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2AFR; H2AFX; H2AFZ; H2AG; H2AH; H2AX; H2AZ; H2AZ1; H2BC1; H2BFU; HIST1H2AA; HIST1H2AB; HIST1H2AD; HIST1H2AE; HIST1H2AG; HIST1H2AH; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; HIST1H2BA; HISTH2AA; hTSH2B; pH2A/f; STBP; TH2A; TH2B; TSH2B; TSH2B.1
UniProt ID: (Human) Q96QV6, (Human) P0C0S8, (Human) Q96KK5, (Human) Q99878, (Human) P04908, (Human) P20671, (Human) P16104, (Human) P0C0S5, (Human) Q96A08
Entrez Gene ID: (Human) 221613, (Human) 8969, (Human) 85235, (Human) 8329, (Human) 8331, (Human) 8335, (Human) 3013, (Human) 3012, (Human) 3014, (Human) 3015, (Human) 255626
DNA binding
structural constituent of chromatin
protein heterodimerization activity
protein binding
enzyme binding
damaged DNA binding
histone binding
chromatin-protein adaptor activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
chromatin DNA binding
nucleosomal DNA binding
heterochromatin assembly
chromatin organization
positive regulation of transcription from RNA polymerase II promoter
cellular response to estradiol stimulus
negative regulation of cell proliferation
protein localization to CENP-A containing chromatin
nucleosome assembly
nucleosome disassembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
DNA damage checkpoint
double-strand break repair via homologous recombination
DNA repair
double-strand break repair
DNA recombination
cellular response to DNA damage stimulus
spermatogenesis
response to ionizing radiation
positive regulation of DNA repair
meiotic cell cycle
protein K63-linked ubiquitination
positive regulation of double-strand break repair via homologous recombination
protein localization to site of double-strand break
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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