Product References
trans-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide Stimulation.
Evidence-based complementary and alternative medicine : eCAM
Fu Y,Yang P,Zhao Y,Zhang L,Zhang Z,Dong X,Wu Z,Xu Y,Chen Y
Fri Apr 08 00:00:00 EDT 2022
miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1.
Frontiers in pharmacology
Cheng XY,Liu JD,Lu XY,Yan X,Huang C,Meng XM,Li J
Thu Oct 01 00:00:00 EDT 2020
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Frontiers in molecular neuroscience
Zhao Z,Zhang L,Guo XD,Cao LL,Xue TF,Zhao XJ,Yang DD,Yang J,Ji J,Huang JY,Sun XL
Wed Sep 30 00:00:00 EDT 2020
EGFRwt/vIII-PKM2-β-catenin cascade affects proliferation and chemo-sensitivity in head and neck squamous cell carcinoma.
American journal of cancer research
Jing C,Qu X,Li Z,Wu C,Zhao M,Wang Y,Sun S,Zhang S,Chen J,Qiao Y,Hu X,Yao X,Jin R,Wang X,Zhang L,Zhou X
Wed Sep 30 00:00:00 EDT 2020
Aryl hydrocarbon receptor activated by benzo (a) pyrene promotes SMARCA6 expression in NSCLC.
American journal of cancer research
Mao C,Wang M,Qian B,Ouyang L,Shi Y,Liu N,Chen L,Xiao D,Wang X,Cao Y,Liu S,Tao Y,Liu W
Wed Sep 30 00:00:00 EDT 2020
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
American journal of translational research
Yao R,Sun X,Xie Y,Liu L,Han D,Yao Y,Li H,Li Z,Xu K
Wed Sep 30 00:00:00 EDT 2020
Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming.
Theranostics
Tan Y,Lin K,Zhao Y,Wu Q,Chen D,Wang J,Liang Y,Li J,Hu J,Wang H,Liu Y,Zhang S,He W,Huang Q,Hu X,Yao Z,Liang B,Liao W,Shi M
Fri Sep 06 00:00:00 EDT 2019
HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway.
Urology
Fan Y,Ou L,Fan J,Li L,Wu X,Luo C,Gao Y,Niu L
Wed May 01 00:00:00 EDT 2019
CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression.
Acta pharmacologica Sinica
Fu XH,Zhang X,Yang H,Xu XW,Hu ZL,Yan J,Zheng XL,Wei RR,Zhang ZQ,Tang SR,Geng MY,Huang X
Wed May 01 00:00:00 EDT 2019
Knockdown of cathepsin D protects dopaminergic neurons against neuroinflammation-mediated neurotoxicity through inhibition of NF-κB signalling pathway in Parkinson's disease model.
Clinical and experimental pharmacology & physiology
Gan P,Xia Q,Hang G,Zhou Y,Qian X,Wang X,Ding L
Mon Apr 01 00:00:00 EDT 2019
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Free radical biology & medicine
Xu LL,Wu YF,Yan F,Li CC,Dai Z,You QD,Jiang ZY,Di B
Mon Apr 01 00:00:00 EDT 2019
Blockade of YAP alleviates hepatic fibrosis through accelerating apoptosis and reversion of activated hepatic stellate cells.
Molecular immunology
Yu HX,Yao Y,Bu FT,Chen Y,Wu YT,Yang Y,Chen X,Zhu Y,Wang Q,Pan XY,Meng XM,Huang C,Li J
Fri Mar 01 00:00:00 EST 2019
Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis.
The FEBS journal
Chen YX,Zhu DY,Gao J,Xu ZL,Tao SC,Yin WJ,Zhang YL,Gao YS,Zhang CQ
Fri Mar 01 00:00:00 EST 2019
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Diabetes
Kong Q,Li N,Cheng H,Zhang X,Cao X,Qi T,Dai L,Zhang Z,Chen X,Li C,Li Y,Xue B,Fang L,Liu L,Ding Z
Fri Feb 01 00:00:00 EST 2019
CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang X,Zhao Y,Jia X,Wang C,Wu Y,Zhang L,Chang Y,Wei W
Fri Feb 01 00:00:00 EST 2019
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Medical microbiology and immunology
Zhang K,Shi MJ,Niu Z,Chen X,Wei JY,Miao ZW,Zhao WD,Chen YH
Fri Feb 01 00:00:00 EST 2019
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Biochimica et biophysica acta. Molecular basis of disease
Yuan C,Guo X,Zhou Q,Du F,Jiang W,Zhou X,Liu P,Chi T,Ji X,Gao J,Chen C,Lang H,Xu J,Liu D,Yang Y,Qiu S,Tang X,Chen G,Zou L
Tue Jan 01 00:00:00 EST 2019
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Scientific reports
Wang S,Xie T,Sun S,Wang K,Liu B,Wu X,Ding W
Wed Dec 12 00:00:00 EST 2018
Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.
Iranian journal of basic medical sciences
Wang Y,Hai B,Ai L,Cao Y,Li R,Li H,Li Y
Sat Dec 01 00:00:00 EST 2018
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Phytotherapy research : PTR
Li Y,Fu S,Li E,Sun X,Xu H,Meng Y,Wang X,Chen Y,Xie C,Geng S,Wu J,Zhong C,Xu P
Sat Dec 01 00:00:00 EST 2018
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Journal of agricultural and food chemistry
Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z
Wed Nov 14 00:00:00 EST 2018
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response.
Cell biology international
Yu B,Zhao Y,Zhang H,Xie D,Nie W,Shi K
Thu Nov 01 00:00:00 EDT 2018
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation.
Oxidative medicine and cellular longevity
Xu LL,Liu T,Wang L,Li L,Wu YF,Li CC,Di B,You QD,Jiang ZY
Fri Oct 26 00:00:00 EDT 2018
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.
Nature communications
Wang S,Lin Y,Yuan X,Li F,Guo L,Wu B
Fri Oct 12 00:00:00 EDT 2018
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Molecules (Basel, Switzerland)
Ge L,Cui Y,Cheng K,Han J
Thu Oct 11 00:00:00 EDT 2018
Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop.
Colloids and surfaces. B, Biointerfaces
Yu Y,Shen X,Liu J,Hu Y,Ran Q,Mu C,Cai K
Mon Oct 01 00:00:00 EDT 2018
BRMS1L suppresses ovarian cancer metastasis via inhibition of the β-catenin-wnt pathway.
Experimental cell research
Cao P,Zhao S,Sun Z,Jiang N,Shang Y,Wang Y,Gu J,Li S
Mon Oct 01 00:00:00 EDT 2018
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Cell
Huang X,Yan J,Zhang M,Wang Y,Chen Y,Fu X,Wei R,Zheng XL,Liu Z,Zhang X,Yang H,Hao B,Shen YY,Su Y,Cong X,Huang M,Tan M,Ding J,Geng M
Thu Sep 20 00:00:00 EDT 2018
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Biochemical and biophysical research communications
Sheng Z,Xu Y,Wang S,Yuan Y,Huang T,Lu P
Mon Sep 10 00:00:00 EDT 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 EDT 2018
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
Neurobiology of disease
He J,Liu H,Zhong J,Guo Z,Wu J,Zhang H,Huang Z,Jiang L,Li H,Zhang Z,Liu L,Wu Y,Qi L,Sun X,Cheng C
Sat Sep 01 00:00:00 EDT 2018
Anticancer effect of histone deacetylase inhibitor scriptaid as a single agent for hepatocellular carcinoma.
Bioscience reports
Liu L,Sun X,Xie Y,Zhuang Y,Yao R,Xu K
Fri Aug 31 00:00:00 EDT 2018
Thymol alleviates lipopolysaccharide-stimulated inflammatory response via downregulation of RhoA-mediated NF-κB signalling pathway in human peritoneal mesothelial cells.
European journal of pharmacology
Wang Q,Cheng F,Xu Y,Zhang J,Qi J,Liu X,Wang R
Wed Aug 15 00:00:00 EDT 2018
Epstein-Barr Virus miR-BART6-3p Inhibits the RIG-I Pathway.
Journal of innate immunity
Lu Y,Qin Z,Wang J,Zheng X,Lu J,Zhang X,Wei L,Peng Q,Zheng Y,Ou C,Ye Q,Xiong W,Li G,Fu Y,Yan Q,Ma J
Tue Jul 24 00:00:00 EDT 2018
The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation.
Investigative ophthalmology & visual science
Yuan Y,Li M,To CH,Lam TC,Wang P,Yu Y,Chen Q,Hu X,Ke B
Mon Jul 02 00:00:00 EDT 2018
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
The Journal of biological chemistry
Yan T,Zhang A,Shi F,Chang F,Mei J,Liu Y,Zhu Y
Fri Jun 29 00:00:00 EDT 2018
The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice.
The Journal of biological chemistry
Zuo X,Rong B,Li L,Lv R,Lan F,Tong MH
Fri Jun 15 00:00:00 EDT 2018
Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat model of donation after cardiac death.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
He W,Ye S,Zeng C,Xue S,Hu X,Zhang X,Gao S,Xiong Y,He X,Vivalda S,Li L,Wang Y,Ye Q
Tue Jun 05 00:00:00 EDT 2018
JMJD3 is involved in neutrophil membrane proteinase 3 overexpression during the hyperinflammatory response in early sepsis.
International immunopharmacology
Chen Y,Liu Z,Pan T,Chen E,Mao E,Chen Y,Tan R,Wang X,Tian R,Liu J,Qu H
Fri Jun 01 00:00:00 EDT 2018
Mitotic Phosphorylation of SENP3 Regulates DeSUMOylation of Chromosome-Associated Proteins and Chromosome Stability.
Cancer research
Wei B,Huang C,Liu B,Wang Y,Xia N,Fan Q,Chen GQ,Cheng J
Tue May 01 00:00:00 EDT 2018
Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology.
Journal of cell science
Thompson LW,Morrison KD,Shirran SL,Groen EJN,Gillingwater TH,Botting CH,Sleeman JE
Tue Apr 17 00:00:00 EDT 2018
27-Hydroxycholesterol Inhibits Sterol Regulatory Element-Binding Protein 1 Activation and Hepatic Lipid Accumulation in Mice.
Obesity (Silver Spring, Md.)
Li D,Long W,Huang R,Chen Y,Xia M
Sun Apr 01 00:00:00 EDT 2018
Role of Peroxiredoxin 2 in the Protection Against Ferrous Sulfate-Induced Oxidative and Inflammatory Injury in PC12 Cells.
Cellular and molecular neurobiology
Xu W,Li F,Xu Z,Sun B,Cao J,Liu Y
Sun Apr 01 00:00:00 EDT 2018
The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1.
Molecular cancer
Zhao Y,Liu Y,Lin L,Huang Q,He W,Zhang S,Dong S,Wen Z,Rao J,Liao W,Shi M
Tue Mar 06 00:00:00 EST 2018
Key Role of TFEB Nucleus Translocation for Silver Nanoparticle-Induced Cytoprotective Autophagy.
Small (Weinheim an der Bergstrasse, Germany)
Lin J,Liu Y,Wu H,Huang Z,Ma J,Guo C,Gao F,Jin P,Wei P,Zhang Y,Liu L,Zhang R,Qiu L,Gu N,Wen L
Thu Mar 01 00:00:00 EST 2018
Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells.
Circulation research
He J,Bao Q,Zhang Y,Liu M,Lv H,Liu Y,Yao L,Li B,Zhang C,He S,Zhai G,Zhu Y,Liu X,Zhang K,Wang XJ,Zou MH,Zhu Y,Ai D
Fri Feb 16 00:00:00 EST 2018
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Journal of experimental & clinical cancer research : CR
Yuan G,Chen X,Liu Z,Wei W,Shu Q,Abou-Hamdan H,Jiang L,Li X,Chen R,Désaubry L,Zhou F,Xie D
Wed Feb 07 00:00:00 EST 2018
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
Toxicology letters
He X,Yuan W,Li Z,Hou Y,Liu F,Feng J
Thu Feb 01 00:00:00 EST 2018
CDK5-mediated phosphorylation of Sirt2 contributes to depressive-like behavior induced by social defeat stress.
Biochimica et biophysica acta. Molecular basis of disease
Zhang Z,Zhang P,Qi GJ,Jiao FJ,Wang QZ,Yan JG,He F,Zhang Q,Lv ZX,Peng X,Cai HW,Chen X,Sun N,Tian B
Thu Feb 01 00:00:00 EST 2018
Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.
Neurobiology of disease
Stanic J,Mellone M,Napolitano F,Racca C,Zianni E,Minocci D,Ghiglieri V,Thiolat ML,Li Q,Longhi A,De Rosa A,Picconi B,Bezard E,Calabresi P,Di Luca M,Usiello A,Gardoni F
Fri Dec 01 00:00:00 EST 2017
Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer.
Journal of experimental & clinical cancer research : CR
Ling Z,Wang X,Tao T,Zhang L,Guan H,You Z,Lu K,Zhang G,Chen S,Wu J,Qian J,Liu H,Xu B,Chen M
Wed Nov 15 00:00:00 EST 2017
YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63-GPX2 Axis and ROS Accumulation.
Cancer research
Huang H,Zhang W,Pan Y,Gao Y,Deng L,Li F,Li F,Ma X,Hou S,Xu J,Li P,Li X,Hu G,Li C,Chen H,Zhang L,Ji H
Wed Nov 01 00:00:00 EDT 2017
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway.
Oncotarget
Yan S,Wei X,Xu S,Sun H,Wang W,Liu L,Jiang X,Zhang Y,Che Y
Fri Oct 06 00:00:00 EDT 2017
Triptolide induces DNA breaks, activates caspase-3-dependent apoptosis and sensitizes B-cell lymphoma to poly(ADP-ribose) polymerase 1 and phosphoinositide 3-kinase inhibitors.
Oncology letters
Guan J,Zhao Q,Lv J,Zhang Z,Sun S,Mao W
Sun Oct 01 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury.
Oncotarget
Xu W,Li F,Liu Z,Xu Z,Sun B,Cao J,Liu Y
Tue Sep 19 00:00:00 EDT 2017
TSPAN31 is a critical regulator on transduction of survival and apoptotic signals in hepatocellular carcinoma cells.
FEBS letters
Wang J,Zhou Y,Li D,Sun X,Deng Y,Zhao Q
Fri Sep 01 00:00:00 EDT 2017
Kaiso protects human umbilical vein endothelial cells against apoptosis by differentially regulating the expression of B-cell CLL/lymphoma 2 family members.
Scientific reports
Xue X,Zhang J,Lan H,Xu Y,Wang H
Wed Aug 02 00:00:00 EDT 2017
Tert-butylhydroquinone protects PC12 cells against ferrous sulfate-induced oxidative and inflammatory injury via the Nrf2/ARE pathway.
Chemico-biological interactions
Xu W,Li F,Xu Z,Sun B,Cao J,Liu Y
Tue Aug 01 00:00:00 EDT 2017
CDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP+-induced Parkinson's disease model.
Scientific reports
Jiao FJ,Wang QZ,Zhang P,Yan JG,Zhang Z,He F,Zhang Q,Lv ZX,Peng X,Cai HW,Tian B
Mon Jul 17 00:00:00 EDT 2017
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang X,Tang S,Dai C,Li D,Zhang S,Deng S,Zhou Y,Xiao X
Sat Jul 01 00:00:00 EDT 2017
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Cell death & disease
Jiang H,Wang Y,Ai M,Wang H,Duan Z,Wang H,Zhao L,Yu J,Ding Y,Wang S
Thu Jun 08 00:00:00 EDT 2017
BTP2, a Store-Operated Calcium Channel Inhibitor, Attenuates Lung Ischemia-Reperfusion Injury in Rats.
Inflammation
Zhang W,Qi Z,Wang Y
Thu Jun 01 00:00:00 EDT 2017
Aspirin suppresses the abnormal lipid metabolism in liver cancer cells via disrupting an NFκB-ACSL1 signaling.
Biochemical and biophysical research communications
Yang G,Wang Y,Feng J,Liu Y,Wang T,Zhao M,Ye L,Zhang X
Sat May 06 00:00:00 EDT 2017
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Wei H,Xu Z,Liu F,Wang F,Wang X,Sun X,Li J
Mon May 01 00:00:00 EDT 2017
Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline.
Neurotoxicity research
Wang HT,Huang FL,Hu ZL,Zhang WJ,Qiao XQ,Huang YQ,Dai RP,Li F,Li CQ
Mon May 01 00:00:00 EDT 2017
Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients.
Hepatology (Baltimore, Md.)
Xiang D,Cheng Z,Liu H,Wang X,Han T,Sun W,Li X,Yang W,Chen C,Xia M,Liu N,Yin S,Jin G,Lee T,Dong L,Hu H,Wang H,Ding J
Mon May 01 00:00:00 EDT 2017
Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells.
Scientific reports
Yan Y,Zhao W,Huang Y,Tong H,Xia Y,Jiang Q,Qin J
Mon Apr 10 00:00:00 EDT 2017
Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy.
Scientific reports
Li T,Hu J,Gao F,Du X,Chen Y,Wu Q
Tue Apr 04 00:00:00 EDT 2017
Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy.
Biomaterials
Wang Q,Jiang H,Li Y,Chen W,Li H,Peng K,Zhang Z,Sun X
Sat Apr 01 00:00:00 EDT 2017
miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia.
Oncology reports
Lyu X,Li J,Yun X,Huang R,Deng X,Wang Y,Chen Y,Xiao G
Wed Mar 01 00:00:00 EST 2017
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Cell death & disease
Cheng W,Qi Y,Tian L,Wang B,Huang W,Chen Y
Thu Feb 23 00:00:00 EST 2017
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
BioMed research international
Liu J,Chen Q,Jian Z,Xiong X,Shao L,Jin T,Zhu X,Wang L
Thu Feb 09 00:00:00 EST 2017
Genetic variants in microRNAs predict non-small cell lung cancer prognosis in Chinese female population in a prospective cohort study.
Oncotarget
Lingzi X,Zhihua Y,Xuelian L,Yangwu R,Haibo Z,Yuxia Z,Baosen Z
Tue Dec 13 00:00:00 EST 2016
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
International immunopharmacology
Sun B,Gao L,Ahsan A,Chu P,Song Y,Li H,Zhang Z,Lin Y,Peng J,Song Z,Wang S,Tang Z
Tue Nov 01 00:00:00 EDT 2016
Compositional Analysis of Asymmetric and Symmetric Dimethylated H3R2 Using Liquid Chromatography-Tandem Mass Spectrometry-Based Targeted Proteomics.
Analytical chemistry
Xu Q,Xu F,Liu L,Chen Y
Tue Sep 06 00:00:00 EDT 2016
Molecular similarity guided optimization of novel Nrf2 activators with 1,2,4-oxadiazole core.
Bioorganic & medicinal chemistry
Xu LL,Zhang X,Jiang ZY,You QD
Mon Aug 15 00:00:00 EDT 2016
Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression.
Oncotarget
Cheng W,Tian L,Wang B,Qi Y,Huang W,Li H,Chen YJ
Tue Jul 26 00:00:00 EDT 2016
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
PloS one
Gao Z,Han Y,Hu Y,Wu X,Wang Y,Zhang X,Fu J,Zou X,Zhang J,Chen X,Jose PA,Lu X,Zeng C
Mon Jul 25 00:00:00 EDT 2016
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
Oncotarget
Huo Y,Zheng Z,Chen Y,Wang Q,Zhang Z,Deng H
Tue Jul 19 00:00:00 EDT 2016
Downregulation of ACE2/Ang-(1-7)/Mas axis promotes breast cancer metastasis by enhancing store-operated calcium entry.
Cancer letters
Yu C,Tang W,Wang Y,Shen Q,Wang B,Cai C,Meng X,Zou F
Fri Jul 01 00:00:00 EDT 2016
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Scientific reports
Ding C,Zhao Y,Shi X,Zhang N,Zu G,Li Z,Zhou J,Gao D,Lv L,Tian X,Yao J
Mon Jun 27 00:00:00 EDT 2016
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
The Journal of biological chemistry
Chen Y,Pan K,Wang P,Cao Z,Wang W,Wang S,Hu N,Xue J,Li H,Jiang W,Li G,Zhang X
Fri Jun 10 00:00:00 EDT 2016
S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proceedings of the National Academy of Sciences of the United States of America
Jayaram H,Hoelper D,Jain SU,Cantone N,Lundgren SM,Poy F,Allis CD,Cummings R,Bellon S,Lewis PW
Tue May 31 00:00:00 EDT 2016
Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents.
Nucleic acids research
Zhang PY,Li G,Deng ZJ,Liu LY,Chen L,Tang JZ,Wang YQ,Cao ST,Fang YX,Wen F,Xu Y,Chen X,Shi KQ,Li WF,Xie C,Tang KF
Thu May 05 00:00:00 EDT 2016
Early ketamine exposure results in cardiac enlargement and heart dysfunction in Xenopus embryos.
BMC anesthesiology
Guo R,Liu G,Du M,Shi Y,Jiang P,Liu X,Liu L,Liu J,Xu Y
Mon Apr 18 00:00:00 EDT 2016
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.
Biochemical and biophysical research communications
Ma ZY,Zhong ZG,Qiu MY,Zhong YH,Zhang WX
Fri Mar 18 00:00:00 EDT 2016
Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus.
eLife
Dinamarca MC,Guzzetti F,Karpova A,Lim D,Mitro N,Musardo S,Mellone M,Marcello E,Stanic J,Samaddar T,Burguière A,Caldarelli A,Genazzani AA,Perroy J,Fagni L,Canonico PL,Kreutz MR,Gardoni F,Di Luca M
Tue Mar 15 00:00:00 EDT 2016
IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB.
International journal of molecular medicine
Gao Q,Liu Y,Wu Y,Zhao Q,Wang L,Gao S,Wen W,Zhang W,Guo N,Zhou J,Yuan Z
Mon Feb 01 00:00:00 EST 2016
Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.
Oncology reports
Gao L,Xu Z,Wang Y,Sun B,Song Z,Yang B,Liu X,Lin Y,Peng J,Han G,Wang S,Tang Z
Mon Feb 01 00:00:00 EST 2016
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Chemico-biological interactions
Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z
Mon Jan 25 00:00:00 EST 2016
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Chemico-biological interactions
Liao H,Bao X,Zhu J,Qu J,Sun Y,Ma X,Wang E,Guo X,Kang Q,Zhen Y
Sat Dec 05 00:00:00 EST 2015
SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.
Apoptosis : an international journal on programmed cell death
Gao L,Wang Y,Xu Z,Li X,Wu J,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z
Tue Dec 01 00:00:00 EST 2015
Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice.
Scientific reports
Qian Z,Wu Z,Huang L,Qiu H,Wang L,Li L,Yao L,Kang K,Qu J,Wu Y,Luo J,Liu JJ,Yang Y,Yang W,Gou D
Mon Nov 30 00:00:00 EST 2015
The Steroid Hormone 20-Hydroxyecdysone Up-regulates Ste-20 Family Serine/Threonine Kinase Hippo to Induce Programmed Cell Death.
The Journal of biological chemistry
Dong DJ,Jing YP,Liu W,Wang JX,Zhao XF
Fri Oct 09 00:00:00 EDT 2015
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
The Journal of biological chemistry
Li H,Liu Q,Wang Z,Fang R,Shen Y,Cai X,Gao Y,Li Y,Zhang X,Ye L
Fri Sep 11 00:00:00 EDT 2015
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
PLoS genetics
Deng J,Yang M,Chen Y,Chen X,Liu J,Sun S,Cheng H,Li Y,Bigio EH,Mesulam M,Xu Q,Du S,Fushimi K,Zhu L,Wu JY
Tue Sep 01 00:00:00 EDT 2015
Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship Study.
Journal of medicinal chemistry
Xu LL,Zhu JF,Xu XL,Zhu J,Li L,Xi MY,Jiang ZY,Zhang MY,Liu F,Lu MC,Bao QC,Li Q,Zhang C,Wei JL,Zhang XJ,Zhang LS,You QD,Sun HP
Thu Jul 23 00:00:00 EDT 2015
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
International journal of molecular medicine
Shi X,Chen G,Liu X,Qiu Y,Yang S,Zhang Y,Fang X,Zhang C,Liu X
Thu Jan 01 00:00:00 EST 2015
Role of NSD1 in H2O2-induced GSTM3 suppression.
Cellular signalling
Chu G,Li Y,Dong X,Liu J,Zhao Y
Mon Dec 01 00:00:00 EST 2014
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
Molecular and cellular biochemistry
Tao H,Li H,Su Y,Feng D,Wang X,Zhang C,Ma H,Hu Q
Mon Sep 01 00:00:00 EDT 2014
Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability.
Cardiovascular diabetology
Tian D,Qiu Y,Zhan Y,Li X,Zhi X,Wang X,Yin L,Ning Y
Wed Nov 21 00:00:00 EST 2012
The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells.
The Journal of biological chemistry
Liu S,Li L,Zhang Y,Zhang Y,Zhao Y,You X,Lin Z,Zhang X,Ye L
Fri Aug 31 00:00:00 EDT 2012
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
The Biochemical journal
Gong K,Xie J,Yi H,Li W
Tue May 01 00:00:00 EDT 2012
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