Invitrogen

Human Fibrinogen Native Protein

Product Details

RP-43142

Applications	Tested Dilution	Publications
Control (Ctrl)	Assay-dependent	-
Miscellaneous PubMed (Misc)	-	View 2 publications 2 publications

Product Specifications
Species	Human
Published species	Not Applicable
Expression System	Human
Molecular weight	340 kDa
Class	Native
Type	Protein
Conjugate	Unconjugated
Form	Liquid
Concentration	4.3 mg/mL
Purification	Affinity chromatography
Storage buffer	0.01M sodium phosphate/0.01M sodium citrate, pH 7.3
Contains	no preservative
Storage conditions	-80° C, Avoid Freeze/Thaw Cycles

Product Specific Information

RP-43142 contains native human Fibrinogen protein.

RP-43142 may be used as a positive control in many immunological assays.

The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.

This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Target Information

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Surface Area to Volume Ratio of Electrospun Polydioxanone Templates Regulates the Adsorption of Soluble Proteins from Human Serum.

Bioengineering (Basel, Switzerland)

Fetz AE,Fantaziu CA,Smith RA,Radic MZ,Bowlin GL

Sat Aug 31 00:00:00 EDT 2019

Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid.

International journal of molecular epidemiology and genetics

Richens JL,Vere KA,Light RA,Soria D,Garibaldi J,Smith AD,Warden D,Wilcock G,Bajaj N,Morgan K,O'Shea P

Tue Jun 24 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: epididymis secretory sperm binding protein Li 78p; fibg; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen, A alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; MGC119422; MGC119423; MGC119425; testicular tissue protein Li 70

Gene Aliases: FGA; FGB; FGG; Fib2; HEL-S-78p; PRO2061

UniProt ID: (Human) P02671, (Human) P02675, (Human) P02679

Entrez Gene ID: (Human) 2243, (Human) 2244, (Human) 2266

Molecular Function: intercellular signal molecule