This peptide corresponds to 14 amino acids near the amino terminus of human LZTR1.
PEP-1016 can be used as a blocking peptide with polyclonal antibody PA5-20902.
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
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Protein Aliases: leucine-zipper-like transcription regulator 1; Leucine-zipper-like transcriptional regulator 1; LZTR-1; MGC21205
Gene Aliases: BTBD29; LZTR-1; LZTR1; NS10; SWNTS2; TCFL2
UniProt ID: (Human) Q8N653
Entrez Gene ID: (Human) 8216