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Product Details
RP-75679
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
Assay-dependent | - |
Control (Ctrl) |
Assay-dependent | - |
| Product Specifications | |
|---|---|
Species |
Human |
Expression System |
E. coli |
Amino acid sequence |
Human PON2 recombinant protein contains an N-terminal His-tag |
Tag |
His-tag |
Class |
Recombinant |
Type |
Protein |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.10 mg/mL |
Purification |
purified |
Storage buffer |
20mM tris HCl, pH 8, with 50% glycerol |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
This product contains purified recombinant human Paraoxonase 2 protein with an N-terminal hexahistidine tag.
This product may be used as a positive control in many immunological assays.
Target Information
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A esterase 2; A-esterase 2; Aromatic esterase 2; arylesterase 2; paraoxonase nirs; PON 2; Serum aryldialkylphosphatase 2; Serum paraoxonase/arylesterase 2
Gene Aliases: PON2
UniProt ID: (Human) Q15165
Entrez Gene ID: (Human) 5445
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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