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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues L(9) L L L T S E I D L P V K R R A(24) of human Humanin.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4358 detects Humanin from human samples.
PA1-4358 has been successfully used in Western blot procedures.
The PA1-4358 immunogen is a synthetic peptide corresponding to residues L(9) L L L T S E I D L P V K R R A(24) of human Humanin.
A gene, Humanin, encodes a short polypeptide and abolishes death of neuronal cells caused by multiple different types of familial Alzheimer's disease genes and by Abeta amyloid, without effect on death by Q79 or superoxide dismutase-1 mutants. This polypeptide serves as a molecular clue for the development of new therapeutics for Alzheimer's disease targeting neuroprotection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.