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Hyaluronidase3 Polyclonal Antibody
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Product Details
BS-5889R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Hyaluronidase3, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hyal-3; Hyaluronidase; hyaluronidase 3; Hyaluronidase-3; hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; LuCa-3; LUCA14; Lung carcinoma protein 3; Minna14; unnamed protein product
Gene Aliases: HYAL-3; HYAL3; Hyl3; LUCA-3; LUCA3
UniProt ID: (Human) O43820, (Mouse) Q8VEI3, (Rat) Q76HM9
Entrez Gene ID: (Human) 8372, (Mouse) 109685, (Rat) 300993
ovarian follicle atresia
carbohydrate metabolic process
inflammatory response
single fertilization
penetration of zona pellucida
response to virus
hyaluronan catabolic process
response to antibiotic
cartilage development
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to UV-B
negative regulation of ovarian follicle development
positive regulation of acrosomal vesicle exocytosis
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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