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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 14 amino acid peptide from near the carboxy terminus of human IA-6.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is rat thymus tissue lysate.
PA5-20824 can be used with blocking peptide PEP-0938.
IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
INSM2 variant 1; insulinoma-associated 2; insulinoma-associated protein 2; insulinoma-associated protein IA-6; methylated in liver tumor 1; mlt 1; Nbla106, IA-6, IA6, mlt1; zinc finger protein IA-6
IA-6; IA6; INSM2; Mlt1; Nbla106