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Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (IHC) |
1:50-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human IA-6 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.4 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2642603 |
Immunogen sequence: KHLSTHEAGS ARALAPGFGS ERGAPLAFAC PLCGAHFPTA DIREKHRLWH AVREELLLPA LAGAPPETSG PSGPSDGSAQ QIFSCKHCPS TF
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: INSM2 variant 1; insulinoma-associated 2; Insulinoma-associated protein 2; insulinoma-associated protein IA-6; Zinc finger protein IA-6
Gene Aliases: IA-6; IA6; INSM2; mlt1; Nbla106
UniProt ID: (Human) Q96T92
Entrez Gene ID: (Human) 84684
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