PA5-27436 targets Iba1 in FACS, ICC/IF, IHC-P and WB applications and shows reactivity with Human and mouse samples. For IHC-P, heat mediated antigen retrieval using 10mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0) is suggested.
The PA5-27436 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 147 of Human Iba1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: AIF-1; Allograft inflammatory factor 1; allograft inflammatory factor-1 splice variant Hara-1; Iba; IBA1; interferon gamma responsive transcript; ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; IRT-1; Protein G1; testis specific
Gene Aliases: AI607846; AIF-1; AIF1; D17H6S50E; G1; IBA1; IRT-1; IRT1