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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 223 of Human ICA1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30066 targets ICA1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30066 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 223 of Human ICA1.
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
69 kDa islet cell autoantigen; diabetes mellitus type I autoantigen; ICA69; ICAp69; islet cell autoantigen 1; islet cell autoantigen 1 isoform; islet cell autoantigen 1, 69kDa; islet cell autoantigen p69; p69; testicular tissue protein Li 162
ICA1; ICA69; ICAp69