Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Intercellular adhesion molecule-1 (ICAM-1) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.
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Protein Aliases: CD54; ICAM-1; Icam1; Intercellular adhesion molecule 1; MALA-2; MyD10
Gene Aliases: CD54; ICAM; Icam-1; Icam1; Ly-47; MALA-2