The antibody detects endogenous levels of total ICAM-4 / CD242 protein.
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an alkylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD242; CD242 antigen; ICAM-4; Intercellular adhesion molecule 4; intercellular adhesion molecule 4 (LW blood group); intercellular adhesion molecule 4 isoform 3 anitgen LWa; Landsteiner-Wiener blood group antigen a; Landsteiner-Wiener blood group glycoprotein; LW; LW blood group protein
Gene Aliases: CD242; ICAM4; LW
UniProt ID: (Human) Q14773
Entrez Gene ID: (Human) 3386