Immunogen sequence: MNREGAPGKSP EEMYIQQKVR VLLMLRKMGS NLTASEEEFL RTYAGVVNSQ LSQLPPHSID QGAEDVVMAF SRSETEDRR
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 99%.
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: Beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
Gene Aliases: CTNNBIP1; ICAT
UniProt ID: (Human) Q9NSA3
Entrez Gene ID: (Human) 56998