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Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Interactor of little elongator complex ELL subunit 1; Little elongation complex subunit 1
Gene Aliases: C77245; ICE1; KIAA0947; mKIAA0947
UniProt ID: (Human) Q9Y2F5, (Mouse) E9Q286
Entrez Gene ID: (Human) 23379, (Mouse) 218333
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