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Invitrogen
ICK Polyclonal Antibody
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Product Details
PA5-51513
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ICK. Recombinant protein control fragment (Product #RP-93677).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VGHPLGSTTQ NLQDSEKPQK GILEKAGPPP YIKPVPPAQP PAKPHTRISS RQHQASQPPL HLTYPYKAEV SRTDHPSHLQ EDKPSPLLFP SLHNKHPQSK ITAGLEHKNG EIKPKSRRR
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 63%.
Target Information
ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ciliogenesis associated kinase 1; hICK; iciliogenesis associated kinase 1; intestinal cell (MAK-like) kinase; Intestinal cell kinase; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK; MRK; protein kinase; serine/threonine protein kinase; Serine/threonine-protein kinase ICK; unnamed protein product
Gene Aliases: CILK1; ECO; EJM10; hICK; ICK; KIAA0936; LCK2; MRK
UniProt ID: (Human) Q9UPZ9
Entrez Gene ID: (Human) 22858
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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