Immunogen sequence: TVWRFFRDRT EEEEISLIHF FGEEYLEYKK RVPTGLPFIK
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
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Protein Aliases: HSTE14; Isoprenylcysteine carboxylmethyltransferase; MST098; MSTP098; PCCMT; PCMT; PPMT; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
Gene Aliases: HSTE14; ICMT; MST098; MSTP098; PCCMT; PCMT; PPMT
UniProt ID: (Human) O60725
Entrez Gene ID: (Human) 23463