Immunogen sequence: KAAMFTAGSN FNHVVQNEKS DTHTLVTSGV YAWFRHPSYV GWFYWSIGTQ VMLCNPICGV SYALTVWRFF RDRTEEEEIS LIHFFGEEYL EYKKRVPTGL PFIKGVKVDL; Positive Samples: U-87MG, K-562, HeLa, THP-1, Mouse testis, Mouse lung, Rat testis; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: farnesyl cysteine carboxyl methyltransferase; Isoprenylcysteine carboxylmethyltransferase; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
Gene Aliases: 1700008E11Rik; C80758; fcmt; Gm13095; HSTE14; ICMT; MST098; MSTP098; OTTMUSG00000010406; PCCMT; PCMT; PPMT; STE14