Invitrogen

ID1 Polyclonal Antibody

Advanced Verification
View all (29) ID1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Tech Support
Datasheet
Protocols
Questions & Answers
Tech Support
Datasheet
Protocols
Questions & Answers
Tech Support
ID1 Polyclonal Antibody

Product Details

PA5-101010

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ID1(Accession P41134), corresponding to amino acid residues I99-D149.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2850486

Product Specific Information

Antibody detects endogenous levels of total Id1.

Target Information

ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. It has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: bHLHb24; Class B basic helix-loop-helix protein 24; dJ857M17.1.2; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); DNA-binding protein inhibitor ID-1; Inhibitor of differentiation 1; Inhibitor of DNA binding 1; Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation); inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)

View more View less

Gene Aliases: AI323524; BHLHB24; D2Wsu140e; ID; Id-1; ID1; ID125A; Idb1

View more View less

UniProt ID: (Human) P41134, (Rat) P41135

View more View less

Entrez Gene ID: (Human) 3397, (Rat) 25261, (Mouse) 15901

View more View less

Function(s)
transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding protein homodimerization activity protein self-association protein N-terminus binding proteasome binding protein dimerization activity DNA-binding transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter angiogenesis endothelial cell morphogenesis transcription, DNA-templated transforming growth factor beta receptor signaling pathway brain development heart development circadian rhythm negative regulation of transcription by transcription factor localization positive regulation of gene expression neuron differentiation BMP signaling pathway protein destabilization positive regulation of actin filament bundle assembly collagen metabolic process cell-abiotic substrate adhesion negative regulation of apoptotic process regulation of MAPK cascade negative regulation of sequence-specific DNA binding transcription factor activity blood vessel endothelial cell migration negative regulation of endothelial cell differentiation negative regulation of osteoblast differentiation regulation of angiogenesis negative regulation of transcription, DNA-templated response to antibiotic blood vessel morphogenesis positive regulation of epithelial cell proliferation negative regulation of dendrite morphogenesis lung morphogenesis lung vasculature development cellular response to epidermal growth factor stimulus negative regulation of protein homodimerization activity cellular response to peptide negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding cellular response to dopamine cellular response to nerve growth factor stimulus response to organic cyclic compound negative regulation of protein binding negative regulation of DNA binding cellular response to transforming growth factor beta stimulus regulation of vasculature development regulation of transcription, DNA-templated multicellular organism development rhythmic process
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support