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Invitrogen
ID2 Polyclonal Antibody
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FIGURE: 1 / 6
ID2 Antibody (PA5-120004) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human fetal skeletal muscle tissue using ID2 Polyclonal Antibody (Product # PA5-120004). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the ID2 antibody at a ... View More
Product Details
PA5-120004
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within C-terminal human ID2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
Positive Control: NCCIT cell lysates, human fetal skeletal muscle tissue, human kidney tissue, mouse colon tissue, mouse lung tissue, HepG2.
Subcellular Location: Cytoplasm, Nucleus.
Target Information
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of a number of cell types including natural killer cell, erythroid precursors, as well as, CD8+ and CD4+ T-cell. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins, and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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