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Proteintech
ID4 Polyclonal Antibody
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Product Details
21803-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ID4 fusion protein Ag16883
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MKAVSPVRPS GRKAPSGCGG GELALRCLAE HGHSLGGSAA AAAAAAAARC KAAEAAADEP ALCLQCDMND
Target Information
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHb27; Class B basic helix-loop-helix protein 27; DNA-binding protein inhibitor ID-4; Inhibitor of differentiation 4; Inhibitor of DNA binding 4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; inhibitor of DNA binding 4, HLH protein
Gene Aliases: BHLHB27; Id-4; ID4; IDB4
UniProt ID: (Human) P47928, (Mouse) P41139
Entrez Gene ID: (Human) 3400, (Rat) 291023, (Mouse) 15904
G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
positive regulation of neuroblast proliferation
neuroblast proliferation
brain development
circadian rhythm
protein localization
cell proliferation
positive regulation of cell proliferation
positive regulation of gene expression
hippocampus development
cerebral cortex neuron differentiation
central nervous system neuron differentiation
central nervous system myelination
neuron differentiation
fat cell differentiation
negative regulation of fat cell differentiation
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
astrocyte differentiation
oligodendrocyte differentiation
negative regulation of astrocyte differentiation
negative regulation of oligodendrocyte differentiation
prostate gland morphogenesis
prostate gland epithelium morphogenesis
prostate gland stromal morphogenesis
seminal vesicle morphogenesis
cellular protein localization
positive regulation of osteoblast differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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