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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • IDE Antibodies

          Bioss

          IDE Polyclonal Antibody

          View all (33) IDE antibodies

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          Cite IDE Polyclonal Antibody

          IDE Polyclonal Antibody

          Product Details

          BS-0018M

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human IDE, amino acids 491-590.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Abeta-degrading protease; FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin

          View more View less

          Gene Aliases: 1300012G03Rik; 4833415K22Rik; AA675336; AI507533; IDE; INSDEGM; INSULYSIN

          View more View less

          UniProt ID: (Human) P14735, (Rat) P35559

          View more View less

          Entrez Gene ID: (Human) 3416, (Rat) 25700, (Mouse) 15925

          View more View less

          Function(s)
          beta-amyloid binding virus receptor activity glycoprotein binding metalloendopeptidase activity receptor binding protein binding ATP binding zinc ion binding ATPase activity beta-endorphin binding peptide binding protein homodimerization activity ubiquitin binding insulin binding peptidase activity peptide hormone binding nucleotide binding catalytic activity metallopeptidase activity hydrolase activity metal ion binding metalloprotease
          Process(es)
          proteolysis insulin receptor signaling pathway determination of adult lifespan bradykinin catabolic process ubiquitin homeostasis protein processing positive regulation of protein oligomerization hormone catabolic process negative regulation of proteolysis viral entry into host cell beta-amyloid metabolic process protein homooligomerization protein homotetramerization protein heterooligomerization proteolysis involved in cellular protein catabolic process insulin metabolic process insulin catabolic process peptide catabolic process cellular protein catabolic process metabolic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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