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Invitrogen
IDE Polyclonal Antibody
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Product Details
PA5-18754
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QQYNYDRDNIE) corresponding to the internal amino acids of Ide (aa 914-924).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin
Gene Aliases: 1300012G03Rik; 4833415K22Rik; AA675336; AI507533; Ide; INSDEGM
UniProt ID: (Rat) P35559
Entrez Gene ID: (Rat) 25700, (Mouse) 15925
beta-amyloid binding
glycoprotein binding
metalloendopeptidase activity
receptor binding
ATP binding
peptidase activity
zinc ion binding
ATPase activity
peptide hormone binding
beta-endorphin binding
peptide binding
protein homodimerization activity
ubiquitin binding
insulin binding
nucleotide binding
catalytic activity
metallopeptidase activity
hydrolase activity
metal ion binding
metalloprotease
proteolysis
determination of adult lifespan
bradykinin catabolic process
ubiquitin homeostasis
positive regulation of protein oligomerization
hormone catabolic process
peptide catabolic process
cellular protein catabolic process
negative regulation of proteolysis
beta-amyloid metabolic process
protein homooligomerization
protein homotetramerization
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
insulin metabolic process
insulin catabolic process
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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