Product References
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Journal of virology
Zhu Z,Zhang M,Yuan L,Xu Y,Zhou H,Lian Z,Liu P,Li X
Tue Jan 31 00:00:00 EST 2023
Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses.
Nature communications
Deng S,He W,Gong AY,Li M,Wang Y,Xia Z,Zhang XT,Huang Pacheco AS,Naqib A,Jenkins M,Swanson PC,Drescher KM,Strauss-Soukup JK,Belshan M,Chen XM
Thu Mar 16 00:00:00 EDT 2023
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Signal transduction and targeted therapy
Zheng W,Zhou Z,Rui Y,Ye R,Xia F,Guo F,Liu X,Su J,Lou M,Yu XF
Fri Feb 24 00:00:00 EST 2023
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Microbiology spectrum
Zhang J,Fang P,Ren J,Xia S,Zhang H,Zhu X,Ding T,Xiao S,Fang L
Tue Mar 28 00:00:00 EDT 2023
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Microbiology spectrum
Zhang J,Fang P,Ren J,Xia S,Zhang H,Zhu X,Ding T,Xiao S,Fang L
Tue Mar 28 00:00:00 EDT 2023
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Microbiology spectrum
Zhang J,Fang P,Ren J,Xia S,Zhang H,Zhu X,Ding T,Xiao S,Fang L
Tue Mar 28 00:00:00 EDT 2023
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Microbiology spectrum
Zhang J,Fang P,Ren J,Xia S,Zhang H,Zhu X,Ding T,Xiao S,Fang L
Tue Mar 28 00:00:00 EDT 2023
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
The EMBO journal
Yi J,Wang L,Hu GS,Zhang YY,Du J,Ding JC,Ji X,Shen HF,Huang HH,Ye F,Liu W
Mon May 15 00:00:00 EDT 2023
IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway.
Viruses
Chen L,Li X,Deng Y,Bi Y,Yan Z,Yang Y,Zhang X,Li H,Xie J,Feng R
Tue Mar 28 00:00:00 EDT 2023
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages.
Journal of innate immunity
Aparici-Herraiz I,Sánchez-Sánchez G,Batlle C,Rehues P,López-Serrat M,Valverde-Estrella L,Lloberas J,Celada A
Tue Dec 26 00:00:00 EST 2023
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses.
Proceedings of the National Academy of Sciences of the United States of America
Carlson RJ,Leiken MD,Guna A,Hacohen N,Blainey PC
Tue Apr 18 00:00:00 EDT 2023
RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency.
The EMBO journal
Stok JE,Oosenbrug T,Ter Haar LR,Gravekamp D,Bromley CP,Zelenay S,Reis e Sousa C,van der Veen AG
Tue Mar 15 00:00:00 EDT 2022
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Clinical cancer research : an official journal of the American Association for Cancer Research
Hiatt JB,Sandborg H,Garrison SM,Arnold HU,Liao SY,Norton JP,Friesen TJ,Wu F,Sutherland KD,Rienhoff HY,Martins R,Houghton AM,Srivastava S,MacPherson D
Fri Oct 14 00:00:00 EDT 2022
Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells.
Viruses
Wang D,Wang R,Li K
Wed Jan 05 00:00:00 EST 2022
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
International journal of molecular sciences
Sun X,Quan L,Chen R,Liu D
Sun Oct 02 00:00:00 EDT 2022
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
International journal of molecular sciences
Sun X,Quan L,Chen R,Liu D
Sun Oct 02 00:00:00 EDT 2022
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
International journal of molecular sciences
Sun X,Quan L,Chen R,Liu D
Sun Oct 02 00:00:00 EDT 2022
STING1 is essential for an RNA-virus triggered autophagy.
Autophagy
Zhang R,Qin X,Yang Y,Zhu X,Zhao S,Zhang Z,Su Q,Zhao Z,Yin X,Meng X,Zhang Z,Li Y
Fri Apr 01 00:00:00 EDT 2022
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
bioRxiv : the preprint server for biology
Jalloh S,Olejnik J,Berrigan J,Nisa A,Suder EL,Akiyama H,Lei M,Tyagi S,Bushkin Y,Mühlberger E,Gummuluru S
Wed Mar 30 00:00:00 EDT 2022
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy.
Journal of virology
Zhang R,Lin H,You Q,Zhang Z,Bai L,Chen F,Zhu X,Zhang Z,Li Y
Wed Oct 26 00:00:00 EDT 2022
Systematic Analysis of Molecular Subtypes Based on the Expression Profile of Immune-Related Genes in Pancreatic Cancer.
Oxidative medicine and cellular longevity
Ke M
Tue Dec 27 00:00:00 EST 2022
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
PLoS pathogens
Jalloh S,Olejnik J,Berrigan J,Nisa A,Suder EL,Akiyama H,Lei M,Ramaswamy S,Tyagi S,Bushkin Y,Mühlberger E,Gummuluru S
Sat Oct 01 00:00:00 EDT 2022
Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses.
PLoS pathogens
Mikhalkevich N,O'Carroll IP,Tkavc R,Lund K,Sukumar G,Dalgard CL,Johnson KR,Li W,Wang T,Nath A,Iordanskiy S
Mon Feb 01 00:00:00 EST 2021
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
BMC veterinary research
Zheng J,Xu Y,Khan A,Sun P,Sun Y,Fan K,Yin W,Wang S,Li H,Sun N
Thu Sep 30 00:00:00 EDT 2021
Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection.
Frontiers in cellular and infection microbiology
Charman M,McFarlane S,Wojtus JK,Sloan E,Dewar R,Leeming G,Al-Saadi M,Hunter L,Carroll MW,Stewart JP,Digard P,Hutchinson E,Boutell C
Mon Oct 18 00:00:00 EDT 2021
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Cell reports
Shen Y,Tang K,Chen D,Hong M,Sun F,Wang S,Ke Y,Wu T,Sun R,Qian J,Du Y
Tue Jun 22 00:00:00 EDT 2021
HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.
Frontiers in microbiology
Li X,Ma R,Wu B,Niu Y,Li H,Li D,Xie J,Idris A,Feng R
Wed Dec 15 00:00:00 EST 2021
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Cell stem cell
Guallar D,Fuentes-Iglesias A,Souto Y,Ameneiro C,Freire-Agulleiro O,Pardavila JA,Escudero A,Garcia-Outeiral V,Moreira T,Saenz C,Xiong H,Liu D,Xiao S,Hou Y,Wu K,Torrecilla D,Hartner JC,Blanco MG,Lee LJ,López M,Walkley CR,Wang J,Fidalgo M
Thu Aug 06 00:00:00 EDT 2020
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Cell stem cell
Guallar D,Fuentes-Iglesias A,Souto Y,Ameneiro C,Freire-Agulleiro O,Pardavila JA,Escudero A,Garcia-Outeiral V,Moreira T,Saenz C,Xiong H,Liu D,Xiao S,Hou Y,Wu K,Torrecilla D,Hartner JC,Blanco MG,Lee LJ,López M,Walkley CR,Wang J,Fidalgo M
Thu Aug 06 00:00:00 EDT 2020
ALS-associated genes in SCA2 mouse spinal cord transcriptomes.
Human molecular genetics
Scoles DR,Dansithong W,Pflieger LT,Paul S,Gandelman M,Figueroa KP,Rigo F,Bennett CF,Pulst SM
Sat Jun 27 00:00:00 EDT 2020
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
Science advances
Dhanwani R,Takahashi M,Mathews IT,Lenzi C,Romanov A,Watrous JD,Pieters B,Hedrick CC,Benedict CA,Linden J,Nilsson R,Jain M,Sharma S
Wed Jul 01 00:00:00 EDT 2020
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
Radiation research
Lee AK,Pan D,Bao X,Hu M,Li F,Li CY
Wed Apr 01 00:00:00 EDT 2020
Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response.
Antiviral research
Yu P,Li Y,Li Y,Miao Z,Wang Y,Peppelenbosch MP,Pan Q
Thu Oct 01 00:00:00 EDT 2020
Ribosome biogenesis restricts innate immune responses to virus infection and DNA.
eLife
Bianco C,Mohr I
Mon Dec 16 00:00:00 EST 2019
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Genes & development
Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I
Sat Dec 01 00:00:00 EST 2018
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Genes & development
Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I
Sat Dec 01 00:00:00 EST 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.
Proteomics
Shang J,Xia T,Han QQ,Zhao X,Hu MM,Shu HB,Guo L
Mon Jan 01 00:00:00 EST 2018
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.
Proteomics
Shang J,Xia T,Han QQ,Zhao X,Hu MM,Shu HB,Guo L
Mon Jan 01 00:00:00 EST 2018
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction.
Nature communications
Akiyama H,Miller CM,Ettinger CR,Belkina AC,Snyder-Cappione JE,Gummuluru S
Mon Aug 27 00:00:00 EDT 2018
MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation.
Nature communications
Zhou P,Ding X,Wan X,Liu L,Yuan X,Zhang W,Hui X,Meng G,Xiao H,Li B,Zhong J,Hou F,Deng L,Zhang Y
Wed Mar 28 00:00:00 EDT 2018
MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation.
Nature communications
Zhou P,Ding X,Wan X,Liu L,Yuan X,Zhang W,Hui X,Meng G,Xiao H,Li B,Zhong J,Hou F,Deng L,Zhang Y
Wed Mar 28 00:00:00 EDT 2018
TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
The Journal of experimental medicine
Lang X,Tang T,Jin T,Ding C,Zhou R,Jiang W
Wed Feb 01 00:00:00 EST 2017
TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
The Journal of experimental medicine
Lang X,Tang T,Jin T,Ding C,Zhou R,Jiang W
Wed Feb 01 00:00:00 EST 2017
ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65.
Cell death & disease
Meng J,Yao Z,He Y,Zhang R,Zhang Y,Yao X,Yang H,Chen L,Zhang Z,Zhang H,Bao X,Hu G,Wu T,Cheng J
Thu Jun 08 00:00:00 EDT 2017
ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65.
Cell death & disease
Meng J,Yao Z,He Y,Zhang R,Zhang Y,Yao X,Yang H,Chen L,Zhang Z,Zhang H,Bao X,Hu G,Wu T,Cheng J
Thu Jun 08 00:00:00 EDT 2017
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Journal of virology
Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G
Tue Nov 15 00:00:00 EST 2016
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Journal of virology
Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G
Tue Nov 15 00:00:00 EST 2016
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism.
mBio
Wang Y,Liu L
Tue Feb 09 00:00:00 EST 2016
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism.
mBio
Wang Y,Liu L
Tue Feb 09 00:00:00 EST 2016
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015