Product References
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Frontiers in immunology
Li C,Du S,Tian M,Wang Y,Bai J,Tan P,Liu W,Yin R,Wang M,Jiang Y,Li Y,Zhu N,Zhu Y,Li T,Wu S,Jin N,He F
Fri Mar 29 00:00:00 EDT 2019
IFITM3 directly engages and shuttles incoming virus particles to lysosomes.
Nature chemical biology
Spence JS,He R,Hoffmann HH,Das T,Thinon E,Rice CM,Peng T,Chandran K,Hang HC
Fri Mar 01 00:00:00 EST 2019
IFITM3 directly engages and shuttles incoming virus particles to lysosomes.
Nature chemical biology
Spence JS,He R,Hoffmann HH,Das T,Thinon E,Rice CM,Peng T,Chandran K,Hang HC
Fri Mar 01 00:00:00 EST 2019
Functional Mapping of Regions Involved in the Negative Imprinting of Virion Particle Infectivity and in Target Cell Protection by Interferon-Induced Transmembrane Protein 3 against HIV-1.
Journal of virology
Appourchaux R,Delpeuch M,Zhong L,Burlaud-Gaillard J,Tartour K,Savidis G,Brass A,Etienne L,Roingeard P,Cimarelli A
Tue Jan 15 00:00:00 EST 2019
Functional Mapping of Regions Involved in the Negative Imprinting of Virion Particle Infectivity and in Target Cell Protection by Interferon-Induced Transmembrane Protein 3 against HIV-1.
Journal of virology
Appourchaux R,Delpeuch M,Zhong L,Burlaud-Gaillard J,Tartour K,Savidis G,Brass A,Etienne L,Roingeard P,Cimarelli A
Tue Jan 15 00:00:00 EST 2019
The β4 subunit of Cav1.2 channels is required for an optimal interferon response in cardiac muscle cells.
Science signaling
Tammineni ER,Carrillo ED,Soto-Acosta R,Angel-Ambrocio AH,García MC,Bautista-Carbajal P,Del Angel RM,Sánchez JA
Tue Dec 11 00:00:00 EST 2018
Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells.
Cell stem cell
Petrillo C,Thorne LG,Unali G,Schiroli G,Giordano AMS,Piras F,Cuccovillo I,Petit SJ,Ahsan F,Noursadeghi M,Clare S,Genovese P,Gentner B,Naldini L,Towers GJ,Kajaste-Rudnitski A
Thu Dec 06 00:00:00 EST 2018
Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells.
Cell stem cell
Petrillo C,Thorne LG,Unali G,Schiroli G,Giordano AMS,Piras F,Cuccovillo I,Petit SJ,Ahsan F,Noursadeghi M,Clare S,Genovese P,Gentner B,Naldini L,Towers GJ,Kajaste-Rudnitski A
Thu Dec 06 00:00:00 EST 2018
IFITM3 Restricts Human Metapneumovirus Infection.
The Journal of infectious diseases
McMichael TM,Zhang Y,Kenney AD,Zhang L,Zani A,Lu M,Chemudupati M,Li J,Yount JS
Fri Oct 05 00:00:00 EDT 2018
Role of MxB in Alpha Interferon-Mediated Inhibition of HIV-1 Infection.
Journal of virology
Xu B,Pan Q,Liang C
Sat Sep 01 00:00:00 EDT 2018
The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor Usage.
Viruses
Yu J,Liu SL
Tue Aug 07 00:00:00 EDT 2018
The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor Usage.
Viruses
Yu J,Liu SL
Tue Aug 07 00:00:00 EDT 2018
Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus.
mBio
Kühnl A,Musiol A,Heitzig N,Johnson DE,Ehrhardt C,Grewal T,Gerke V,Ludwig S,Rescher U
Tue Jul 24 00:00:00 EDT 2018
Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.
Journal of proteome research
Thinon E,Fernandez JP,Molina H,Hang HC
Fri May 04 00:00:00 EDT 2018
Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Tsai CY,Chi HC,Chi LM,Yang HY,Tsai MM,Lee KF,Huang HW,Chou LF,Cheng AJ,Yang CW,Wang CS,Lin KH
Tue May 01 00:00:00 EDT 2018
A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery.
Retrovirology
Roesch F,OhAinle M,Emerman M
Tue Mar 20 00:00:00 EDT 2018
The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity.
The Journal of biological chemistry
McMichael TM,Zhang L,Chemudupati M,Hach JC,Kenney AD,Hang HC,Yount JS
Fri Dec 29 00:00:00 EST 2017
The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity.
The Journal of biological chemistry
McMichael TM,Zhang L,Chemudupati M,Hach JC,Kenney AD,Hang HC,Yount JS
Fri Dec 29 00:00:00 EST 2017
Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.
Antioxidants & redox signaling
Sareila O,Hagert C,Kelkka T,Linja M,Xu B,Kihlberg J,Holmdahl R
Wed Dec 20 00:00:00 EST 2017
Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation.
PLoS pathogens
Shan J,Zhao B,Shan Z,Nie J,Deng R,Xiong R,Tsun A,Pan W,Zhao H,Chen L,Jin Y,Qian Z,Lui K,Liang R,Li D,Sun B,Lavillette D,Xu K,Li B
Fri Dec 01 00:00:00 EST 2017
IFITM3 requires an amphipathic helix for antiviral activity.
EMBO reports
Chesarino NM,Compton AA,McMichael TM,Kenney AD,Zhang L,Soewarna V,Davis M,Schwartz O,Yount JS
Sun Oct 01 00:00:00 EDT 2017
Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV.
PloS one
Wilkins J,Zheng YM,Yu J,Liang C,Liu SL
Wed Jul 26 00:00:00 EDT 2017
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.
The EMBO journal
Monel B,Compton AA,Bruel T,Amraoui S,Burlaud-Gaillard J,Roy N,Guivel-Benhassine F,Porrot F,Génin P,Meertens L,Sinigaglia L,Jouvenet N,Weil R,Casartelli N,Demangel C,Simon-Lorière E,Moris A,Roingeard P,Amara A,Schwartz O
Wed Jun 14 00:00:00 EDT 2017
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.
The EMBO journal
Monel B,Compton AA,Bruel T,Amraoui S,Burlaud-Gaillard J,Roy N,Guivel-Benhassine F,Porrot F,Génin P,Meertens L,Sinigaglia L,Jouvenet N,Weil R,Casartelli N,Demangel C,Simon-Lorière E,Moris A,Roingeard P,Amara A,Schwartz O
Wed Jun 14 00:00:00 EDT 2017
Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection.
PloS one
Muñoz-Moreno R,Cuesta-Geijo MÁ,Martínez-Romero C,Barrado-Gil L,Galindo I,García-Sastre A,Alonso C
Mon Mar 27 00:00:00 EDT 2017
Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection.
PloS one
Muñoz-Moreno R,Cuesta-Geijo MÁ,Martínez-Romero C,Barrado-Gil L,Galindo I,García-Sastre A,Alonso C
Mon Mar 27 00:00:00 EDT 2017
Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins.
Journal of virology
Wrensch F,Hoffmann M,Gärtner S,Nehlmeier I,Winkler M,Pöhlmann S
Sun Jan 15 00:00:00 EST 2017
The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses.
Journal of virology
Poddar S,Hyde JL,Gorman MJ,Farzan M,Diamond MS
Sat Oct 01 00:00:00 EDT 2016
The Interferon-Stimulated Gene Ifitm3 Restricts West Nile Virus Infection and Pathogenesis.
Journal of virology
Gorman MJ,Poddar S,Farzan M,Diamond MS
Thu Sep 15 00:00:00 EDT 2016
Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling.
Research in veterinary science
Zeng X,Wang S,Chi X,Chen SL,Huang S,Lin Q,Xie B,Chen JL
Mon Feb 01 00:00:00 EST 2016
IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.
Cell reports
Yu J,Li M,Wilkins J,Ding S,Swartz TH,Esposito AM,Zheng YM,Freed EO,Liang C,Chen BK,Liu SL
Tue Oct 06 00:00:00 EDT 2015
IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.
Cell reports
Yu J,Li M,Wilkins J,Ding S,Swartz TH,Esposito AM,Zheng YM,Freed EO,Liang C,Chen BK,Liu SL
Tue Oct 06 00:00:00 EDT 2015
Wif1 and Ifitm3 gene expression preferentially altered in the colon mucosa of benzo[a]pyrene pre-treated mice following exposure to dextran sulfate sodium.
Chemico-biological interactions
Koyama N,Hakura A,Toritsuka N,Sonoda J,Seki Y,Tohyama O,Asakura S,Nakano-Ito K,Hosokawa S
Mon Oct 05 00:00:00 EDT 2015
Expression profile and histological distribution of IFITM1 and IFITM3 during H9N2 avian influenza virus infection in BALB/c mice.
Medical microbiology and immunology
Yu M,Qi W,Huang Z,Zhang K,Ye J,Liu R,Wang H,Ma Y,Liao M,Ning Z
Sat Aug 01 00:00:00 EDT 2015
E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3.
PLoS pathogens
Chesarino NM,McMichael TM,Yount JS
Sat Aug 01 00:00:00 EDT 2015
Muscovy duck reovirus infection rapidly activates host innate immune signaling and induces an effective antiviral immune response involving critical interferons.
Veterinary microbiology
Chen Z,Luo G,Wang Q,Wang S,Chi X,Huang Y,Wei H,Wu B,Huang S,Chen JL
Wed Feb 25 00:00:00 EST 2015
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Cellular microbiology
Zhu X,He Z,Yuan J,Wen W,Huang X,Hu Y,Lin C,Pan J,Li R,Deng H,Liao S,Zhou R,Wu J,Li J,Li M
Thu Jan 01 00:00:00 EST 2015
Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins.
Virology
Qian J,Le Duff Y,Wang Y,Pan Q,Ding S,Zheng YM,Liu SL,Liang C
Thu Jan 01 00:00:00 EST 2015
IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.
Cell host & microbe
Compton AA,Bruel T,Porrot F,Mallet A,Sachse M,Euvrard M,Liang C,Casartelli N,Schwartz O
Wed Dec 10 00:00:00 EST 2014
IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.
Cell host & microbe
Compton AA,Bruel T,Porrot F,Mallet A,Sachse M,Euvrard M,Liang C,Casartelli N,Schwartz O
Wed Dec 10 00:00:00 EST 2014
IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity.
Retrovirology
Tartour K,Appourchaux R,Gaillard J,Nguyen XN,Durand S,Turpin J,Beaumont E,Roch E,Berger G,Mahieux R,Brand D,Roingeard P,Cimarelli A
Tue Nov 25 00:00:00 EST 2014
T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert.
Science (New York, N.Y.)
Ariotti S,Hogenbirk MA,Dijkgraaf FE,Visser LL,Hoekstra ME,Song JY,Jacobs H,Haanen JB,Schumacher TN
Fri Oct 03 00:00:00 EDT 2014
Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.
Journal of virology
Wang S,Chi X,Wei H,Chen Y,Chen Z,Huang S,Chen JL
Fri Aug 01 00:00:00 EDT 2014
Identification of an endocytic signal essential for the antiviral action of IFITM3.
Cellular microbiology
Jia R,Xu F,Qian J,Yao Y,Miao C,Zheng YM,Liu SL,Guo F,Geng Y,Qiao W,Liang C
Tue Jul 01 00:00:00 EDT 2014
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.
Proceedings of the National Academy of Sciences of the United States of America
Zhao X,Guo F,Liu F,Cuconati A,Chang J,Block TM,Guo JT
Tue May 06 00:00:00 EDT 2014
Negative regulation of interferon-induced transmembrane protein 3 by SET7-mediated lysine monomethylation.
The Journal of biological chemistry
Shan Z,Han Q,Nie J,Cao X,Chen Z,Yin S,Gao Y,Lin F,Zhou X,Xu K,Fan H,Qian Z,Sun B,Zhong J,Li B,Tsun A
Fri Dec 06 00:00:00 EST 2013
IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus.
Journal of virology
Mudhasani R,Tran JP,Retterer C,Radoshitzky SR,Kota KP,Altamura LA,Smith JM,Packard BZ,Kuhn JH,Costantino J,Garrison AR,Schmaljohn CS,Huang IC,Farzan M,Bavari S
Thu Aug 01 00:00:00 EDT 2013
Knockdown of interferon-induced transmembrane protein 3 expression suppresses breast cancer cell growth and colony formation and affects the cell cycle.
Oncology reports
Yang M,Gao H,Chen P,Jia J,Wu S
Mon Jul 01 00:00:00 EDT 2013
Identification of host proteins involved in Japanese encephalitis virus infection by quantitative proteomics analysis.
Journal of proteome research
Zhang LK,Chai F,Li HY,Xiao G,Guo L
Fri Jun 07 00:00:00 EDT 2013
TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
Journal of virology
Bertram S,Dijkman R,Habjan M,Heurich A,Gierer S,Glowacka I,Welsch K,Winkler M,Schneider H,Hofmann-Winkler H,Thiel V,Pöhlmann S
Sat Jun 01 00:00:00 EDT 2013
IFITM proteins restrict viral membrane hemifusion.
PLoS pathogens
Li K,Markosyan RM,Zheng YM,Golfetto O,Bungart B,Li M,Ding S,He Y,Liang C,Lee JC,Gratton E,Cohen FS,Liu SL
Tue Jan 01 00:00:00 EST 2013
The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization.
Journal of virology
Jia R,Pan Q,Ding S,Rong L,Liu SL,Geng Y,Qiao W,Liang C
Sat Dec 01 00:00:00 EST 2012
The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization.
Journal of virology
Jia R,Pan Q,Ding S,Rong L,Liu SL,Geng Y,Qiao W,Liang C
Sat Dec 01 00:00:00 EST 2012
IFITM3 restricts the morbidity and mortality associated with influenza.
Nature
Everitt AR,Clare S,Pertel T,John SP,Wash RS,Smith SE,Chin CR,Feeley EM,Sims JS,Adams DJ,Wise HM,Kane L,Goulding D,Digard P,Anttila V,Baillie JK,Walsh TS,Hume DA,Palotie A,Xue Y,Colonna V,Tyler-Smith C,Dunning J,Gordon SB,Smyth RL,Openshaw PJ,Dougan G,Brass AL,Kellam P
Sun Mar 25 00:00:00 EDT 2012
The IFITM proteins inhibit HIV-1 infection.
Journal of virology
Lu J,Pan Q,Rong L,He W,Liu SL,Liang C
Tue Mar 01 00:00:00 EST 2011
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Journal of virology
Weidner JM,Jiang D,Pan XB,Chang J,Block TM,Guo JT
Wed Dec 01 00:00:00 EST 2010
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Journal of virology
Weidner JM,Jiang D,Pan XB,Chang J,Block TM,Guo JT
Wed Dec 01 00:00:00 EST 2010
Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections.
Journal of virology
Jiang D,Weidner JM,Qing M,Pan XB,Guo H,Xu C,Zhang X,Birk A,Chang J,Shi PY,Block TM,Guo JT
Sun Aug 01 00:00:00 EDT 2010