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Proteintech
IFN alpha2 Polyclonal Antibody
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Product Details
32673-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IFN alpha2 fusion protein Eg3079
Conjugate
Form
Liquid
Concentration
500 µg/mL
Amount
75 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: CDLPHTYNLR NKRALKVLAQ MRRLPFLSCL KDRQDFGFPL EKVDNQQIQK AQAIPVLRDL TQQTLNLFTS KASSAAWNAT LLDSFCNDLH QQLNDLQTCL MQQVGVQEPP LTQEDALLAV RKYFHRITVY LREKKHSPCA WEVVRAEVWR ALSSSVNLLP RLSEEKE
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IFN-a; IFN-alpha 1b; IFN-alpha-1/13; IFN-alpha-2; IFNA 2; Interferon; interferon alpha 1b; interferon alpha family, gene 2; interferon alpha-2; interferon alpha-D; Interferon-alpha II; leIF D; RP11-354P17.2
Gene Aliases: Ifa2
Entrez Gene ID: (Mouse) 15965
adaptive immune response
T cell activation involved in immune response
natural killer cell activation involved in immune response
defense response
humoral immune response
cytokine-mediated signaling pathway
B cell differentiation
positive regulation of peptidyl-serine phosphorylation of STAT protein
B cell proliferation
response to exogenous dsRNA
defense response to virus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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