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Proteintech
IFNGR1 Polyclonal Antibody
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Product Details
10808-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IFNGR1 Fusion Protein Ag1114 (189-489 aa encoded by BC005333)
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Amount
79.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TQKEDDCDE IQCQLAIPVS SLNSQYCVSA EGVLHVWGVT TEKSKEVCIT IFNSSIKGSL WIPVVAALLL FLVLSLVFIC FYIKKINPLK EKSIILPKSL ISVVRSATLE TKPESKYVSL ITSYQPFSLE KEVVCEEPLS PATVPGMHTE DNPGKVEHTE ELSSITEVVT TEENIPDVVP GSHLTPIERE SSSPLSSNQS EPGSIALNSY HSRNCSESDH SRNGFDTDSS CLESHSSLSD SEFPPNNKGE IKTEGQELIT VIKAPTSFGY DKPHVLVDLL VDDSGKESLI GYRPTEDSKE FS (189-489 aa encoded by BC005333)
Target Information
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; cytokine receptor; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; IFNgR1; immune interferon receptor 1; Interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor; interferon-gamma receptor alpha chain; unnamed protein product
Gene Aliases: CD119; IFNGR; IFNGR1; IMD27A; IMD27B
UniProt ID: (Human) P15260
Entrez Gene ID: (Human) 3459
microglial cell activation
immune system process
signal transduction
JAK-STAT cascade
response to virus
positive regulation of gene expression
cytokine-mediated signaling pathway
positive regulation of tumor necrosis factor production
type III interferon-mediated signaling pathway
astrocyte activation
defense response to virus
interferon-gamma-mediated signaling pathway
defense response to other organism
cellular response to virus
negative regulation of beta-amyloid clearance
positive regulation of beta-amyloid formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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