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Invitrogen
IFT172 Polyclonal Antibody
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Product Details
PA5-43702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human IFT172 (aa 360-409).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: VKILGKERYL VAHTSETLLL GDLNTNRLSE IAWQGSGGNE KYFFENENVC
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: intraflagellar transport 172 homolog; Intraflagellar transport protein 172 homolog; selective LIM binding factor homolog; unnamed protein product; wimple homolog
Gene Aliases: BBS20; IFT172; KIAA1179; NPHP17; osm-1; RP71; SLB; SRTD10; wim
UniProt ID: (Human) Q9UG01
Entrez Gene ID: (Human) 26160
neural tube formation
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
determination of left/right symmetry
brain development
heart development
epidermis development
regulation of smoothened signaling pathway
dorsal/ventral pattern formation
negative regulation of keratinocyte proliferation
protein processing
spinal cord motor neuron differentiation
neural tube development
cytoplasmic microtubule organization
intraciliary anterograde transport
intraciliary transport
keratinocyte proliferation
cilium organization
negative regulation of smoothened signaling pathway
positive regulation of smoothened signaling pathway
embryonic camera-type eye morphogenesis
negative regulation of epithelial cell proliferation
palate development
limb development
cilium morphogenesis
bone development
hindgut development
left/right axis specification
non-motile cilium assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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