Product References
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 EST 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 EDT 2018
Trisomy 21 Represses Cilia Formation and Function.
Developmental cell
Galati DF,Sullivan KD,Pham AT,Espinosa JM,Pearson CG
Mon Sep 10 00:00:00 EDT 2018
EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.
Nature communications
Kasahara K,Aoki H,Kiyono T,Wang S,Kagiwada H,Yuge M,Tanaka T,Nishimura Y,Mizoguchi A,Goshima N,Inagaki M
Thu Feb 22 00:00:00 EST 2018
Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition.
Biochemical and biophysical research communications
Han SJ,Jung JK,Im SS,Lee SR,Jang BC,Park KM,Kim JI
Mon Feb 05 00:00:00 EST 2018
Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SH,Joo K,Jung EJ,Hong H,Seo J,Kim J
Thu Feb 01 00:00:00 EST 2018
IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.
The Journal of cell biology
Schmid FM,Schou KB,Vilhelm MJ,Holm MS,Breslin L,Farinelli P,Larsen LA,Andersen JS,Pedersen LB,Christensen ST
Tue Jan 02 00:00:00 EST 2018
IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.
The Journal of cell biology
Schmid FM,Schou KB,Vilhelm MJ,Holm MS,Breslin L,Farinelli P,Larsen LA,Andersen JS,Pedersen LB,Christensen ST
Tue Jan 02 00:00:00 EST 2018
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Human molecular genetics
Martin L,Kaci N,Estibals V,Goudin N,Garfa-Traore M,Benoist-Lasselin C,Dambroise E,Legeai-Mallet L
Mon Jan 01 00:00:00 EST 2018
EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.
Proceedings of the National Academy of Sciences of the United States of America
Guen VJ,Chavarria TE,Kröger C,Ye X,Weinberg RA,Lees JA
Tue Dec 05 00:00:00 EST 2017
The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.
Scientific reports
Kurtenbach S,Gießl A,Strömberg S,Kremers J,Atorf J,Rasche S,Neuhaus EM,Hervé D,Brandstätter JH,Asan E,Hatt H,Kilimann MW
Wed Aug 16 00:00:00 EDT 2017
Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.
Molecular biology of the cell
Katoh Y,Michisaka S,Nozaki S,Funabashi T,Hirano T,Takei R,Nakayama K
Sat Apr 01 00:00:00 EDT 2017
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness.
Scientific reports
Nishita M,Park SY,Nishio T,Kamizaki K,Wang Z,Tamada K,Takumi T,Hashimoto R,Otani H,Pazour GJ,Hsu VW,Minami Y
Thu Jan 26 00:00:00 EST 2017
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness.
Scientific reports
Nishita M,Park SY,Nishio T,Kamizaki K,Wang Z,Tamada K,Takumi T,Hashimoto R,Otani H,Pazour GJ,Hsu VW,Minami Y
Thu Jan 26 00:00:00 EST 2017
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi.
Nature communications
Stoetzel C,Bär S,De Craene JO,Scheidecker S,Etard C,Chicher J,Reck JR,Perrault I,Geoffroy V,Chennen K,Strähle U,Hammann P,Friant S,Dollfus H
Thu Nov 24 00:00:00 EST 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.
Proceedings of the National Academy of Sciences of the United States of America
Noda K,Kitami M,Kitami K,Kaku M,Komatsu Y
Tue May 10 00:00:00 EDT 2016
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.
Proceedings of the National Academy of Sciences of the United States of America
Noda K,Kitami M,Kitami K,Kaku M,Komatsu Y
Tue May 10 00:00:00 EDT 2016
Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.
The Journal of cell biology
Inaba H,Goto H,Kasahara K,Kumamoto K,Yonemura S,Inoko A,Yamano S,Wanibuchi H,He D,Goshima N,Kiyono T,Hirotsune S,Inagaki M
Mon Feb 15 00:00:00 EST 2016
IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Vivar OI,Masi G,Carpier JM,Magalhaes JG,Galgano D,Pazour GJ,Amigorena S,Hivroz C,Baldari CT
Tue Jan 12 00:00:00 EST 2016
IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Vivar OI,Masi G,Carpier JM,Magalhaes JG,Galgano D,Pazour GJ,Amigorena S,Hivroz C,Baldari CT
Tue Jan 12 00:00:00 EST 2016
Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish.
Human molecular genetics
Liu F,Chen J,Yu S,Raghupathy RK,Liu X,Qin Y,Li C,Huang M,Liao S,Wang J,Zou J,Shu X,Tang Z,Liu M
Sat Aug 15 00:00:00 EDT 2015
Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells.
Biomolecules & therapeutics
Shin JH,Bae DJ,Kim ES,Kim HB,Park SJ,Jo YK,Jo DS,Jo DG,Kim SY,Cho DH
Wed Jul 01 00:00:00 EDT 2015
BIX-01294-induced autophagy regulates elongation of primary cilia.
Biochemical and biophysical research communications
Shin JH,Kim PS,Kim ES,Park SJ,Jo YK,Hwang JJ,Park TJ,Chang JW,Seo JH,Cho DH
Fri May 01 00:00:00 EDT 2015
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Wed Apr 01 00:00:00 EDT 2015
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Sun Mar 01 00:00:00 EST 2015
Primary cilia signaling mediates intraocular pressure sensation.
Proceedings of the National Academy of Sciences of the United States of America
Luo N,Conwell MD,Chen X,Kettenhofen CI,Westlake CJ,Cantor LB,Wells CD,Weinreb RN,Corson TW,Spandau DF,Joos KM,Iomini C,Obukhov AG,Sun Y
Tue Sep 02 00:00:00 EDT 2014
Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis.
Molecular biology of the cell
Greer YE,Westlake CJ,Gao B,Bharti K,Shiba Y,Xavier CP,Pazour GJ,Yang Y,Rubin JS
Thu May 01 00:00:00 EDT 2014
Functional interaction between autophagy and ciliogenesis.
Nature
Pampliega O,Orhon I,Patel B,Sridhar S,Díaz-Carretero A,Beau I,Codogno P,Satir BH,Satir P,Cuervo AM
Thu Oct 10 00:00:00 EDT 2013
CCDC41 is required for ciliary vesicle docking to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Joo K,Kim CG,Lee MS,Moon HY,Lee SH,Kim MJ,Kweon HS,Park WY,Kim CH,Gleeson JG,Kim J
Tue Apr 09 00:00:00 EDT 2013
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Human molecular genetics
Zhang Q,Seo S,Bugge K,Stone EM,Sheffield VC
Tue May 01 00:00:00 EDT 2012
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.
The Journal of cell biology
Inoko A,Matsuyama M,Goto H,Ohmuro-Matsuyama Y,Hayashi Y,Enomoto M,Ibi M,Urano T,Yonemura S,Kiyono T,Izawa I,Inagaki M
Mon Apr 30 00:00:00 EDT 2012
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.
The Journal of cell biology
Inoko A,Matsuyama M,Goto H,Ohmuro-Matsuyama Y,Hayashi Y,Enomoto M,Ibi M,Urano T,Yonemura S,Kiyono T,Izawa I,Inagaki M
Mon Apr 30 00:00:00 EDT 2012
The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development.
Human molecular genetics
Hurd T,Zhou W,Jenkins P,Liu CJ,Swaroop A,Khanna H,Martens J,Hildebrandt F,Margolis B
Mon Nov 15 00:00:00 EST 2010
