Product References
Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.
PLoS genetics
Bowie E,Norris R,Anderson KV,Goetz SC
Sat Dec 01 00:00:00 EST 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.
Scientific reports
Silva LM,Jacobs DT,Allard BA,Fields TA,Sharma M,Wallace DP,Tran PV
Wed Mar 21 00:00:00 EDT 2018
Intraflagellar transporter protein 140 (IFT140), a component of IFT-A complex, is essential for male fertility and spermiogenesis in mice.
Cytoskeleton (Hoboken, N.J.)
Zhang Y,Liu H,Li W,Zhang Z,Zhang S,Teves ME,Stevens C,Foster JA,Campbell GE,Windle JJ,Hess RA,Pazour GJ,Zhang Z
Thu Feb 01 00:00:00 EST 2018
The small GTPase RSG1 controls a final step in primary cilia initiation.
The Journal of cell biology
Agbu SO,Liang Y,Liu A,Anderson KV
Tue Jan 02 00:00:00 EST 2018
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.
Nature communications
Taulet N,Vitre B,Anguille C,Douanier A,Rocancourt M,Taschner M,Lorentzen E,Echard A,Delaval B
Mon Dec 04 00:00:00 EST 2017
Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.
Developmental biology
Zhang Y,Liu H,Li W,Zhang Z,Shang X,Zhang D,Li Y,Zhang S,Liu J,Hess RA,Pazour GJ,Zhang Z
Fri Dec 01 00:00:00 EST 2017
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation.
The Journal of biological chemistry
Roy K,Jerman S,Jozsef L,McNamara T,Onyekaba G,Sun Z,Marin EP
Fri Oct 27 00:00:00 EDT 2017
The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling.
PloS one
Goetz SC,Bangs F,Barrington CL,Katsanis N,Anderson KV
Fri Sep 08 00:00:00 EDT 2017
Immunofluorescent staining of septins in primary cilia.
Methods in cell biology
Kim MS,Froese CD,Xie H,Trimble WS
Mon Aug 21 00:00:00 EDT 2017
IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Development (Cambridge, England)
Xin D,Christopher KJ,Zeng L,Kong Y,Weatherbee SD
Sat Apr 15 00:00:00 EDT 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.
Scientific reports
Duran I,Taylor SP,Zhang W,Martin J,Forlenza KN,Spiro RP,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Mon Sep 26 00:00:00 EDT 2016
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.
Scientific reports
Duran I,Taylor SP,Zhang W,Martin J,Forlenza KN,Spiro RP,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Mon Sep 26 00:00:00 EDT 2016
IFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome.
Human molecular genetics
Zhang W,Taylor SP,Nevarez L,Lachman RS,Nickerson DA,Bamshad M,Krakow D,Cohn DH
Thu Sep 15 00:00:00 EDT 2016
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells.
The Journal of cell biology
Bernabé-Rubio M,Andrés G,Casares-Arias J,Fernández-Barrera J,Rangel L,Reglero-Real N,Gershlick DC,Fernández JJ,Millán J,Correas I,Miguez DG,Alonso MA
Mon Aug 01 00:00:00 EDT 2016
Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.
Nature cell biology
Raman M,Sergeev M,Garnaas M,Lydeard JR,Huttlin EL,Goessling W,Shah JV,Harper JW
Thu Oct 01 00:00:00 EDT 2015
IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype.
Journal of medical genetics
Perrault I,Halbritter J,Porath JD,Gérard X,Braun DA,Gee HY,Fathy HM,Saunier S,Cormier-Daire V,Thomas S,Attié-Bitach T,Boddaert N,Taschner M,Schueler M,Lorentzen E,Lifton RP,Lawson JA,Garfa-Traore M,Otto EA,Bastin P,Caillaud C,Kaplan J,Rozet JM,Hildebrandt F
Thu Oct 01 00:00:00 EDT 2015
The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.
Nature cell biology
He M,Subramanian R,Bangs F,Omelchenko T,Liem KF,Kapoor TM,Anderson KV
Tue Jul 01 00:00:00 EDT 2014
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Human molecular genetics
Zhang Q,Seo S,Bugge K,Stone EM,Sheffield VC
Tue May 01 00:00:00 EDT 2012