Product References
Fixation methods can differentially affect ciliary protein immunolabeling.
Cilia
Hua K,Ferland RJ
Thu Oct 01 00:00:00 EDT 2020
Fixation methods can differentially affect ciliary protein immunolabeling.
Cilia
Hua K,Ferland RJ
Thu Oct 01 00:00:00 EDT 2020
Chloroquine inhibits human retina pigmented epithelial cell growth and microtubule nucleation by downregulating p150glued.
Journal of cellular physiology
Chen TY,Lien WC,Cheng HL,Kuan TS,Sheu SY,Wang CY
Mon Jul 01 00:00:00 EDT 2019
Failure to reabsorb the primary cilium induces cellular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jeffries EP,Di Filippo M,Galbiati F
Mon Apr 01 00:00:00 EDT 2019
Type I collagen-induced YAP nuclear expression promotes primary cilia growth and contributes to cell migration in confluent mouse embryo fibroblast 3T3-L1 cells.
Molecular and cellular biochemistry
Xu Q,Liu X,Liu W,Hayashi T,Yamato M,Fujisaki H,Hattori S,Tashiro SI,Onodera S,Ikejima T
Tue Jan 01 00:00:00 EST 2019
Malformations in the Murine Kidney Caused by Loss of CENP-F Function.
Anatomical record (Hoboken, N.J. : 2007)
Haley CO,Waters AM,Bader DM
Tue Jan 01 00:00:00 EST 2019
Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling.
Nature communications
Vuong LT,Iomini C,Balmer S,Esposito D,Aaronson SA,Mlodzik M
Thu Dec 13 00:00:00 EST 2018
Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling.
Nature communications
Vuong LT,Iomini C,Balmer S,Esposito D,Aaronson SA,Mlodzik M
Thu Dec 13 00:00:00 EST 2018
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 EST 2018
Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.
PLoS genetics
Bowie E,Norris R,Anderson KV,Goetz SC
Sat Dec 01 00:00:00 EST 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 EDT 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 EDT 2018
Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Abdelhamed ZA,Ryan TA,Fuller M,Coulson-Gilmer C,Abdelmottaleb DI,Wang TL,Kaun JC,Wang P,Hutson R,Wilkinson N,Bell SM,Johnson CA
Mon Oct 01 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility.
Cells
Shamoto N,Narita K,Kubo T,Oda T,Takeda S
Wed Aug 29 00:00:00 EDT 2018
FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia.
Proceedings of the National Academy of Sciences of the United States of America
Honda A,Kita T,Seshadri SV,Misaki K,Ahmed Z,Ladbury JE,Richardson GP,Yonemura S,Ladher RK
Tue Aug 14 00:00:00 EDT 2018
Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis.
The Journal of cell biology
Funabashi T,Katoh Y,Okazaki M,Sugawa M,Nakayama K
Mon Aug 06 00:00:00 EDT 2018
Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis.
The Journal of cell biology
Funabashi T,Katoh Y,Okazaki M,Sugawa M,Nakayama K
Mon Aug 06 00:00:00 EDT 2018
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
The EMBO journal
Viau A,Bienaimé F,Lukas K,Todkar AP,Knoll M,Yakulov TA,Hofherr A,Kretz O,Helmstädter M,Reichardt W,Braeg S,Aschman T,Merkle A,Pfeifer D,Dumit VI,Gubler MC,Nitschke R,Huber TB,Terzi F,Dengjel J,Grahammer F,Köttgen M,Busch H,Boerries M,Walz G,Triantafyllopoulou A,Kuehn EW
Wed Aug 01 00:00:00 EDT 2018
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Human molecular genetics
Barny I,Perrault I,Michel C,Soussan M,Goudin N,Rio M,Thomas S,Attié-Bitach T,Hamel C,Dollfus H,Kaplan J,Rozet JM,Gerard X
Wed Aug 01 00:00:00 EDT 2018
Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.
Oncogene
Lee J,Yi S,Won M,Song YS,Yi HS,Park YJ,Park KC,Kim JT,Chang JY,Lee MJ,Sul HJ,Choi JE,Kim KS,Kero J,Kim J,Shong M
Wed Aug 01 00:00:00 EDT 2018
Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.
Oncogene
Lee J,Yi S,Won M,Song YS,Yi HS,Park YJ,Park KC,Kim JT,Chang JY,Lee MJ,Sul HJ,Choi JE,Kim KS,Kero J,Kim J,Shong M
Wed Aug 01 00:00:00 EDT 2018
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Biophysical journal
Weng RR,Yang TT,Huang CE,Chang CW,Wang WJ,Liao JC
Tue Jul 17 00:00:00 EDT 2018
IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis.
Human genetics
Chekuri A,Guru AA,Biswas P,Branham K,Borooah S,Soto-Hermida A,Hicks M,Khan NW,Matsui H,Alapati A,Raghavendra PB,Roosing S,Sarangapani S,Mathavan S,Telenti A,Heckenlively JR,Riazuddin SA,Frazer KA,Sieving PA,Ayyagari R
Sun Jul 01 00:00:00 EDT 2018
TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms.
Cellular and molecular life sciences : CMLS
Rosengren T,Larsen LJ,Pedersen LB,Christensen ST,Møller LB
Sun Jul 01 00:00:00 EDT 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
The EMBO journal
Wiegering A,Dildrop R,Kalfhues L,Spychala A,Kuschel S,Lier JM,Zobel T,Dahmen S,Leu T,Struchtrup A,Legendre F,Vesque C,Schneider-Maunoury S,Saunier S,Rüther U,Gerhardt C
Tue May 15 00:00:00 EDT 2018
Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
The Journal of cell biology
Vion AC,Alt S,Klaus-Bergmann A,Szymborska A,Zheng T,Perovic T,Hammoutene A,Oliveira MB,Bartels-Klein E,Hollfinger I,Rautou PE,Bernabeu MO,Gerhardt H
Mon May 07 00:00:00 EDT 2018
The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane.
Journal of cell science
Revenkova E,Liu Q,Gusella GL,Iomini C
Fri May 04 00:00:00 EDT 2018
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.
American journal of human genetics
Forbes TA,Howden SE,Lawlor K,Phipson B,Maksimovic J,Hale L,Wilson S,Quinlan C,Ho G,Holman K,Bennetts B,Crawford J,Trnka P,Oshlack A,Patel C,Mallett A,Simons C,Little MH
Thu May 03 00:00:00 EDT 2018
Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.
Biology open
Takei R,Katoh Y,Nakayama K
Mon Apr 30 00:00:00 EDT 2018
Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.
Biology open
Takei R,Katoh Y,Nakayama K
Mon Apr 30 00:00:00 EDT 2018
Centrobin controls primary ciliogenesis in vertebrates.
The Journal of cell biology
Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG
Mon Apr 02 00:00:00 EDT 2018
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.
Scientific reports
Silva LM,Jacobs DT,Allard BA,Fields TA,Sharma M,Wallace DP,Tran PV
Wed Mar 21 00:00:00 EDT 2018
iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu X,Wang J,Gao L,Liu H,Liu C
Tue Mar 06 00:00:00 EST 2018
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Human molecular genetics
Hartill VL,van de Hoek G,Patel MP,Little R,Watson CM,Berry IR,Shoemark A,Abdelmottaleb D,Parkes E,Bacchelli C,Szymanska K,Knoers NV,Scambler PJ,Ueffing M,Boldt K,Yates R,Winyard PJ,Adler B,Moya E,Hattingh L,Shenoy A,Hogg C,Sheridan E,Roepman R,Norris D,Mitchison HM,Giles RH,Johnson CA
Thu Feb 01 00:00:00 EST 2018
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Human molecular genetics
Hartill VL,van de Hoek G,Patel MP,Little R,Watson CM,Berry IR,Shoemark A,Abdelmottaleb D,Parkes E,Bacchelli C,Szymanska K,Knoers NV,Scambler PJ,Ueffing M,Boldt K,Yates R,Winyard PJ,Adler B,Moya E,Hattingh L,Shenoy A,Hogg C,Sheridan E,Roepman R,Norris D,Mitchison HM,Giles RH,Johnson CA
Thu Feb 01 00:00:00 EST 2018
Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SH,Joo K,Jung EJ,Hong H,Seo J,Kim J
Thu Feb 01 00:00:00 EST 2018
CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.
Cell reports
Canning P,Park K,Gonçalves J,Li C,Howard CJ,Sharpe TD,Holt LJ,Pelletier L,Bullock AN,Leroux MR
Tue Jan 23 00:00:00 EST 2018
STED and STORM Superresolution Imaging of Primary Cilia.
Methods in molecular biology (Clifton, N.J.)
Yang TT,Chong WM,Liao JC
Fri Jan 12 00:00:00 EST 2018
Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway.
Oncotarget
Khan NA,Garg AD,Agostinis P,Swinnen JV
Tue Jan 09 00:00:00 EST 2018
Glucose deprivation induces primary cilium formation through mTORC1 inactivation.
Journal of cell science
Takahashi K,Nagai T,Chiba S,Nakayama K,Mizuno K
Mon Jan 08 00:00:00 EST 2018
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
The Journal of experimental medicine
Deng YZ,Cai Z,Shi S,Jiang H,Shang YR,Ma N,Wang JJ,Guan DX,Chen TW,Rong YF,Qian ZY,Zhang EB,Feng D,Zhou QL,Du YN,Liu DP,Huang XX,Liu LM,Chin E,Li DS,Wang XF,Zhang XL,Xie D
Tue Jan 02 00:00:00 EST 2018
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
The Journal of experimental medicine
Deng YZ,Cai Z,Shi S,Jiang H,Shang YR,Ma N,Wang JJ,Guan DX,Chen TW,Rong YF,Qian ZY,Zhang EB,Feng D,Zhou QL,Du YN,Liu DP,Huang XX,Liu LM,Chin E,Li DS,Wang XF,Zhang XL,Xie D
Tue Jan 02 00:00:00 EST 2018
The small GTPase RSG1 controls a final step in primary cilia initiation.
The Journal of cell biology
Agbu SO,Liang Y,Liu A,Anderson KV
Tue Jan 02 00:00:00 EST 2018
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Human molecular genetics
Martin L,Kaci N,Estibals V,Goudin N,Garfa-Traore M,Benoist-Lasselin C,Dambroise E,Legeai-Mallet L
Mon Jan 01 00:00:00 EST 2018
mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
Developmental cell
Wu CC,Hou S,Orr BA,Kuo BR,Youn YH,Ong T,Roth F,Eberhart CG,Robinson GW,Solecki DJ,Taketo MM,Gilbertson RJ,Roussel MF,Han YG
Mon Dec 18 00:00:00 EST 2017
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.
Nature communications
Taulet N,Vitre B,Anguille C,Douanier A,Rocancourt M,Taschner M,Lorentzen E,Echard A,Delaval B
Mon Dec 04 00:00:00 EST 2017
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.
Nature communications
Taulet N,Vitre B,Anguille C,Douanier A,Rocancourt M,Taschner M,Lorentzen E,Echard A,Delaval B
Mon Dec 04 00:00:00 EST 2017
A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies.
Human molecular genetics
Srivastava S,Ramsbottom SA,Molinari E,Alkanderi S,Filby A,White K,Henry C,Saunier S,Miles CG,Sayer JA
Fri Dec 01 00:00:00 EST 2017
A mutation in IFT43 causes non-syndromic recessive retinal degeneration.
Human molecular genetics
Biswas P,Duncan JL,Ali M,Matsui H,Naeem MA,Raghavendra PB,Frazer KA,Arts HH,Riazuddin S,Akram J,Hejtmancik JF,Riazuddin SA,Ayyagari R
Fri Dec 01 00:00:00 EST 2017
Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis.
The Journal of cell biology
Pitaval A,Senger F,Letort G,Gidrol X,Guyon L,Sillibourne J,Théry M
Mon Nov 06 00:00:00 EST 2017
Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination.
eLife
Kasioulis I,Das RM,Storey KG
Mon Oct 23 00:00:00 EDT 2017
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
PLoS genetics
Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC
Sun Oct 01 00:00:00 EDT 2017
Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer's disease by regulating cilia function.
Alzheimer's research & therapy
Hu L,Wang B,Zhang Y
Wed Sep 20 00:00:00 EDT 2017
The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling.
PloS one
Goetz SC,Bangs F,Barrington CL,Katsanis N,Anderson KV
Fri Sep 08 00:00:00 EDT 2017
The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.
EMBO reports
Kohli P,Höhne M,Jüngst C,Bertsch S,Ebert LK,Schauss AC,Benzing T,Rinschen MM,Schermer B
Fri Sep 01 00:00:00 EDT 2017
Missense mutations in the WD40 domain of AHI1 cause non-syndromic retinitis pigmentosa.
Journal of medical genetics
Nguyen TT,Hull S,Roepman R,van den Born LI,Oud MM,de Vrieze E,Hetterschijt L,Letteboer SJF,van Beersum SEC,Blokland EA,Yntema HG,Cremers FPM,van der Zwaag PA,Arno G,van Wijk E,Webster AR,Haer-Wigman L
Fri Sep 01 00:00:00 EDT 2017
Immunofluorescent staining of septins in primary cilia.
Methods in cell biology
Kim MS,Froese CD,Xie H,Trimble WS
Mon Aug 21 00:00:00 EDT 2017
A novel role for primary cilia in airway remodeling.
American journal of physiology. Lung cellular and molecular physiology
Trempus CS,Song W,Lazrak A,Yu Z,Creighton JR,Young BM,Heise RL,Yu YR,Ingram JL,Tighe RM,Matalon S,Garantziotis S
Tue Aug 01 00:00:00 EDT 2017
NEK7 is required for G1 progression and procentriole formation.
Molecular biology of the cell
Gupta A,Tsuchiya Y,Ohta M,Shiratsuchi G,Kitagawa D
Sat Jul 15 00:00:00 EDT 2017
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Scientific reports
Ding J,Shao L,Yao Y,Tong X,Liu H,Yue S,Xie L,Cheng SY
Thu Jul 13 00:00:00 EDT 2017
Primary cilia control the maturation of tubular lumen in renal collecting duct epithelium.
American journal of physiology. Cell physiology
Ernandez T,Komarynets O,Chassot A,Sougoumarin S,Soulié P,Wang Y,Montesano R,Feraille E
Sat Jul 01 00:00:00 EDT 2017
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.
Nature genetics
Lu H,Galeano MCR,Ott E,Kaeslin G,Kausalya PJ,Kramer C,Ortiz-Brüchle N,Hilger N,Metzis V,Hiersche M,Tay SY,Tunningley R,Vij S,Courtney AD,Whittle B,Wühl E,Vester U,Hartleben B,Neuber S,Frank V,Little MH,Epting D,Papathanasiou P,Perkins AC,Wright GD,Hunziker W,Gee HY,Otto EA,Zerres K,Hildebrandt F,Roy S,Wicking C,Bergmann C
Sat Jul 01 00:00:00 EDT 2017
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Journal of cellular physiology
Wang CY,Tsai HL,Syu JS,Chen TY,Su MT
Thu Jun 01 00:00:00 EDT 2017
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Journal of cellular physiology
Wang CY,Tsai HL,Syu JS,Chen TY,Su MT
Thu Jun 01 00:00:00 EDT 2017
USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.
PLoS genetics
Das A,Qian J,Tsang WY
Mon May 01 00:00:00 EDT 2017
IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Development (Cambridge, England)
Xin D,Christopher KJ,Zeng L,Kong Y,Weatherbee SD
Sat Apr 15 00:00:00 EDT 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.
Molecular biology of the cell
Katoh Y,Michisaka S,Nozaki S,Funabashi T,Hirano T,Takei R,Nakayama K
Sat Apr 01 00:00:00 EDT 2017
Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients.
Scientific reports
Oliazadeh N,Gorman KF,Eveleigh R,Bourque G,Moreau A
Tue Mar 14 00:00:00 EDT 2017
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.
Molecular biology of the cell
Funabashi T,Katoh Y,Michisaka S,Terada M,Sugawa M,Nakayama K
Wed Mar 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.
Journal of cell science
Nozaki S,Katoh Y,Terada M,Michisaka S,Funabashi T,Takahashi S,Kontani K,Nakayama K
Wed Feb 01 00:00:00 EST 2017
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Nature communications
Schou KB,Mogensen JB,Morthorst SK,Nielsen BS,Aleliunaite A,Serra-Marques A,Fürstenberg N,Saunier S,Bizet AA,Veland IR,Akhmanova A,Christensen ST,Pedersen LB
Mon Jan 30 00:00:00 EST 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.
Scientific reports
Yu F,Sharma S,Skowronek A,Erdmann KS
Fri Oct 21 00:00:00 EDT 2016
The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.
Scientific reports
Yu F,Sharma S,Skowronek A,Erdmann KS
Fri Oct 21 00:00:00 EDT 2016
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
PLoS genetics
Hong CJ,Hamilton BA
Sat Oct 01 00:00:00 EDT 2016
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
PLoS genetics
Hong CJ,Hamilton BA
Sat Oct 01 00:00:00 EDT 2016
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.
Scientific reports
Duran I,Taylor SP,Zhang W,Martin J,Forlenza KN,Spiro RP,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Mon Sep 26 00:00:00 EDT 2016
A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis.
Developmental cell
Nechipurenko IV,Olivier-Mason A,Kazatskaya A,Kennedy J,McLachlan IG,Heiman MG,Blacque OE,Sengupta P
Mon Sep 12 00:00:00 EDT 2016
Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.
Cell cycle (Georgetown, Tex.)
Siller SS,Burke MC,Li FQ,Takemaru K
Tue Aug 30 00:00:00 EDT 2016
Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.
Cell cycle (Georgetown, Tex.)
Siller SS,Burke MC,Li FQ,Takemaru K
Tue Aug 30 00:00:00 EDT 2016
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells.
The Journal of cell biology
Bernabé-Rubio M,Andrés G,Casares-Arias J,Fernández-Barrera J,Rangel L,Reglero-Real N,Gershlick DC,Fernández JJ,Millán J,Correas I,Miguez DG,Alonso MA
Mon Aug 01 00:00:00 EDT 2016
MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737.
World journal of gastroenterology
Zhao G,Wang T,Huang QK,Pu M,Sun W,Zhang ZC,Ling R,Tao KS
Tue Jun 21 00:00:00 EDT 2016
A Cilia Independent Role of Ift88/Polaris during Cell Migration.
PloS one
Boehlke C,Janusch H,Hamann C,Powelske C,Mergen M,Herbst H,Kotsis F,Nitschke R,Kuehn EW
Fri Jun 17 00:00:00 EDT 2016
A Cilia Independent Role of Ift88/Polaris during Cell Migration.
PloS one
Boehlke C,Janusch H,Hamann C,Powelske C,Mergen M,Herbst H,Kotsis F,Nitschke R,Kuehn EW
Fri Jun 17 00:00:00 EDT 2016
Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.
Biochimica et biophysica acta
Kim JH,Ki SM,Joung JG,Scott E,Heynen-Genel S,Aza-Blanc P,Kwon CH,Kim J,Gleeson JG,Lee JE
Wed Jun 01 00:00:00 EDT 2016
Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia.
The Journal of biological chemistry
Zhong M,Zhao X,Li J,Yuan W,Yan G,Tong M,Guo S,Zhu Y,Jiang Y,Liu Y,Jiang Y
Fri May 27 00:00:00 EDT 2016
Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex.
The Journal of biological chemistry
Katoh Y,Terada M,Nishijima Y,Takei R,Nozaki S,Hamada H,Nakayama K
Fri May 20 00:00:00 EDT 2016
Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex.
The Journal of biological chemistry
Katoh Y,Terada M,Nishijima Y,Takei R,Nozaki S,Hamada H,Nakayama K
Fri May 20 00:00:00 EDT 2016
Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis.
eLife
Wang L,Lee K,Malonis R,Sanchez I,Dynlacht BD
Thu May 05 00:00:00 EDT 2016
Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function.
Scientific reports
Cortés CR,McInerney-Leo AM,Vogel I,Rondón Galeano MC,Leo PJ,Harris JE,Anderson LK,Keith PA,Brown MA,Ramsing M,Duncan EL,Zankl A,Wicking C
Wed Apr 20 00:00:00 EDT 2016
Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.
PloS one
Xu Y,Cao J,Huang S,Feng D,Zhang W,Zhu X,Yan X
Mon Apr 18 00:00:00 EDT 2016
Identification of drugs that restore primary cilium expression in cancer cells.
Oncotarget
Khan NA,Willemarck N,Talebi A,Marchand A,Binda MM,Dehairs J,Rueda-Rincon N,Daniels VW,Bagadi M,Thimiri Govinda Raj DB,Vanderhoydonc F,Munck S,Chaltin P,Swinnen JV
Tue Mar 01 00:00:00 EST 2016
Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis.
Nature communications
Xu Q,Zhang Y,Wei Q,Huang Y,Hu J,Ling K
Fri Feb 26 00:00:00 EST 2016
Biological and Chemical Removal of Primary Cilia Affects Mechanical Activation of Chondrogenesis Markers in Chondroprogenitors and Hypertrophic Chondrocytes.
International journal of molecular sciences
Deren ME,Yang X,Guan Y,Chen Q
Thu Feb 04 00:00:00 EST 2016
Imaging centrosomes and cilia in the mouse kidney.
Methods in cell biology
Hoshi M,Wang J,Jain S,Mahjoub MR
Tue Jan 26 00:00:00 EST 2016
The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity.
Cancer cell
Vo BT,Wolf E,Kawauchi D,Gebhardt A,Rehg JE,Finkelstein D,Walz S,Murphy BL,Youn YH,Han YG,Eilers M,Roussel MF
Mon Jan 11 00:00:00 EST 2016
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.
Cell cycle (Georgetown, Tex.)
Gholkar AA,Senese S,Lo YC,Capri J,Deardorff WJ,Dharmarajan H,Contreras E,Hodara E,Whitelegge JP,Jackson PK,Torres JZ
Mon Dec 28 00:00:00 EST 2015
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.
Cell cycle (Georgetown, Tex.)
Gholkar AA,Senese S,Lo YC,Capri J,Deardorff WJ,Dharmarajan H,Contreras E,Hodara E,Whitelegge JP,Jackson PK,Torres JZ
Mon Dec 28 00:00:00 EST 2015
Proteomics of Primary Cilia by Proximity Labeling.
Developmental cell
Mick DU,Rodrigues RB,Leib RD,Adams CM,Chien AS,Gygi SP,Nachury MV
Mon Nov 23 00:00:00 EST 2015
Identification of a novel MKS locus defined by TMEM107 mutation.
Human molecular genetics
Shaheen R,Almoisheer A,Faqeih E,Babay Z,Monies D,Tassan N,Abouelhoda M,Kurdi W,Al Mardawi E,Khalil MM,Seidahmed MZ,Alnemer M,Alsahan N,Sogaty S,Alhashem A,Singh A,Goyal M,Kapoor S,Alomar R,Ibrahim N,Alkuraya FS
Tue Sep 15 00:00:00 EDT 2015
Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone.
Scientific reports
Yang TT,Su J,Wang WJ,Craige B,Witman GB,Tsou MF,Liao JC
Mon Sep 14 00:00:00 EDT 2015
Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle.
Nature communications
Kim S,Lee K,Choi JH,Ringstad N,Dynlacht BD
Thu Aug 20 00:00:00 EDT 2015
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.
Scientific reports
Ran J,Yang Y,Li D,Liu M,Zhou J
Thu Aug 06 00:00:00 EDT 2015
Ciliary abnormalities in senescent human fibroblasts impair proliferative capacity.
Cell cycle (Georgetown, Tex.)
Breslin L,Prosser SL,Cuffe S,Morrison CG
Tue Jul 21 00:00:00 EDT 2015
Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization.
The Journal of biological chemistry
Kang GM,Han YM,Ko HW,Kim J,Oh BC,Kwon I,Kim MS
Fri Jul 17 00:00:00 EDT 2015
Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.
Human molecular genetics
Caparrós-Martín JA,De Luca A,Cartault F,Aglan M,Temtamy S,Otaify GA,Mehrez M,Valencia M,Vázquez L,Alessandri JL,Nevado J,Rueda-Arenas I,Heath KE,Digilio MC,Dallapiccola B,Goodship JA,Mill P,Lapunzina P,Ruiz-Perez VL
Wed Jul 15 00:00:00 EDT 2015
DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects.
Scientific reports
Kessler K,Wunderlich I,Uebe S,Falk NS,Gießl A,Brandstätter JH,Popp B,Klinger P,Ekici AB,Sticht H,Dörr HG,Reis A,Roepman R,Seemanová E,Thiel CT
Wed Jul 01 00:00:00 EDT 2015
Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome.
Nature communications
Taylor SP,Dantas TJ,Duran I,Wu S,Lachman RS,Nelson SF,Cohn DH,Vallee RB,Krakow D
Tue Jun 16 00:00:00 EDT 2015
The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation.
Journal of cell science
Reales E,Bernabé-Rubio M,Casares-Arias J,Rentero C,Fernández-Barrera J,Rangel L,Correas I,Enrich C,Andrés G,Alonso MA
Mon Jun 15 00:00:00 EDT 2015
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.
Nature communications
Schmidts M,Hou Y,Cortés CR,Mans DA,Huber C,Boldt K,Patel M,van Reeuwijk J,Plaza JM,van Beersum SE,Yap ZM,Letteboer SJ,Taylor SP,Herridge W,Johnson CA,Scambler PJ,Ueffing M,Kayserili H,Krakow D,King SM,Beales PL,Al-Gazali L,Wicking C,Cormier-Daire V,Roepman R,Mitchison HM,Witman GB
Fri Jun 05 00:00:00 EDT 2015
Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.
Science (New York, N.Y.)
Wong YL,Anzola JV,Davis RL,Yoon M,Motamedi A,Kroll A,Seo CP,Hsia JE,Kim SK,Mitchell JW,Mitchell BJ,Desai A,Gahman TC,Shiau AK,Oegema K
Fri Jun 05 00:00:00 EDT 2015
Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation.
Stem cells (Dayton, Ohio)
Dalbay MT,Thorpe SD,Connelly JT,Chapple JP,Knight MM
Mon Jun 01 00:00:00 EDT 2015
Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
Biochemical and biophysical research communications
Hong H,Kim J,Kim J
Fri May 22 00:00:00 EDT 2015
Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
Biochemical and biophysical research communications
Hong H,Kim J,Kim J
Fri May 22 00:00:00 EDT 2015
BIX-01294-induced autophagy regulates elongation of primary cilia.
Biochemical and biophysical research communications
Shin JH,Kim PS,Kim ES,Park SJ,Jo YK,Hwang JJ,Park TJ,Chang JW,Seo JH,Cho DH
Fri May 01 00:00:00 EDT 2015
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
Human molecular genetics
Barbelanne M,Hossain D,Chan DP,Peränen J,Tsang WY
Wed Apr 15 00:00:00 EDT 2015
An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition.
Cell reports
Williams CH,Hempel JE,Hao J,Frist AY,Williams MM,Fleming JT,Sulikowski GA,Cooper MK,Chiang C,Hong CC
Tue Apr 07 00:00:00 EDT 2015
Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways.
Autophagy
Wang S,Livingston MJ,Su Y,Dong Z
Fri Apr 03 00:00:00 EDT 2015
GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.
PLoS biology
Zhang B,Zhang T,Wang G,Wang G,Chi W,Jiang Q,Zhang C
Wed Apr 01 00:00:00 EDT 2015
Centrin2 regulates CP110 removal in primary cilium formation.
The Journal of cell biology
Prosser SL,Morrison CG
Mon Mar 16 00:00:00 EDT 2015
The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes.
Journal of medical genetics
Waters AM,Asfahani R,Carroll P,Bicknell L,Lescai F,Bright A,Chanudet E,Brooks A,Christou-Savina S,Osman G,Walsh P,Bacchelli C,Chapgier A,Vernay B,Bader DM,Deshpande C,O' Sullivan M,Ocaka L,Stanescu H,Stewart HS,Hildebrandt F,Otto E,Johnson CA,Szymanska K,Katsanis N,Davis E,Kleta R,Hubank M,Doxsey S,Jackson A,Stupka E,Winey M,Beales PL
Sun Mar 01 00:00:00 EST 2015
A founder CEP120 mutation in Jeune asphyxiating thoracic dystrophy expands the role of centriolar proteins in skeletal ciliopathies.
Human molecular genetics
Shaheen R,Schmidts M,Faqeih E,Hashem A,Lausch E,Holder I,Superti-Furga A,Mitchison HM,Almoisheer A,Alamro R,Alshiddi T,Alzahrani F,Beales PL,Alkuraya FS
Sun Mar 01 00:00:00 EST 2015
Lineage specificity of primary cilia in the mouse embryo.
Nature cell biology
Bangs FK,Schrode N,Hadjantonakis AK,Anderson KV
Sun Feb 01 00:00:00 EST 2015
DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.
American journal of human genetics
Schueler M,Braun DA,Chandrasekar G,Gee HY,Klasson TD,Halbritter J,Bieder A,Porath JD,Airik R,Zhou W,LoTurco JJ,Che A,Otto EA,Böckenhauer D,Sebire NJ,Honzik T,Harris PC,Koon SJ,Gunay-Aygun M,Saunier S,Zerres K,Bruechle NO,Drenth JP,Pelletier L,Tapia-Páez I,Lifton RP,Giles RH,Kere J,Hildebrandt F
Thu Jan 08 00:00:00 EST 2015
Katanin p80 regulates human cortical development by limiting centriole and cilia number.
Neuron
Hu WF,Pomp O,Ben-Omran T,Kodani A,Henke K,Mochida GH,Yu TW,Woodworth MB,Bonnard C,Raj GS,Tan TT,Hamamy H,Masri A,Shboul M,Al Saffar M,Partlow JN,Al-Dosari M,Alazami A,Alowain M,Alkuraya FS,Reiter JF,Harris MP,Reversade B,Walsh CA
Wed Dec 17 00:00:00 EST 2014
Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy.
Nature genetics
Martin CA,Ahmad I,Klingseisen A,Hussain MS,Bicknell LS,Leitch A,Nürnberg G,Toliat MR,Murray JE,Hunt D,Khan F,Ali Z,Tinschert S,Ding J,Keith C,Harley ME,Heyn P,Müller R,Hoffmann I,Cormier-Daire V,Dollfus H,Dupuis L,Bashamboo A,McElreavey K,Kariminejad A,Mendoza-Londono R,Moore AT,Saggar A,Schlechter C,Weleber R,Thiele H,Altmüller J,Höhne W,Hurles ME,Noegel AA,Baig SM,Nürnberg P,Jackson AP
Mon Dec 01 00:00:00 EST 2014
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Developmental cell
Liew GM,Ye F,Nager AR,Murphy JP,Lee JS,Aguiar M,Breslow DK,Gygi SP,Nachury MV
Mon Nov 10 00:00:00 EST 2014
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Developmental cell
Liew GM,Ye F,Nager AR,Murphy JP,Lee JS,Aguiar M,Breslow DK,Gygi SP,Nachury MV
Mon Nov 10 00:00:00 EST 2014
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 EDT 2014
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 EDT 2014
Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly.
The Journal of cell biology
Taschner M,Kotsis F,Braeuer P,Kuehn EW,Lorentzen E
Mon Oct 27 00:00:00 EDT 2014
Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration.
Human molecular genetics
Karlstetter M,Sorusch N,Caramoy A,Dannhausen K,Aslanidis A,Fauser S,Boesl MR,Nagel-Wolfrum K,Tamm ER,Jägle H,Stoehr H,Wolfrum U,Langmann T
Wed Oct 01 00:00:00 EDT 2014
Basal foot MTOC organizes pillar MTs required for coordination of beating cilia.
Nature communications
Clare DK,Magescas J,Piolot T,Dumoux M,Vesque C,Pichard E,Dang T,Duvauchelle B,Poirier F,Delacour D
Fri Sep 12 00:00:00 EDT 2014
Primary cilia signaling mediates intraocular pressure sensation.
Proceedings of the National Academy of Sciences of the United States of America
Luo N,Conwell MD,Chen X,Kettenhofen CI,Westlake CJ,Cantor LB,Wells CD,Weinreb RN,Corson TW,Spandau DF,Joos KM,Iomini C,Obukhov AG,Sun Y
Tue Sep 02 00:00:00 EDT 2014
Nedd9 restrains renal cystogenesis in Pkd1-/- mice.
Proceedings of the National Academy of Sciences of the United States of America
Nikonova AS,Plotnikova OV,Serzhanova V,Efimov A,Bogush I,Cai KQ,Hensley HH,Egleston BL,Klein-Szanto A,Seeger-Nukpezah T,Golemis EA
Tue Sep 02 00:00:00 EDT 2014
Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain.
PLoS genetics
Cevik S,Sanders AA,Van Wijk E,Boldt K,Clarke L,van Reeuwijk J,Hori Y,Horn N,Hetterschijt L,Wdowicz A,Mullins A,Kida K,Kaplan OI,van Beersum SE,Man Wu K,Letteboer SJ,Mans DA,Katada T,Kontani K,Ueffing M,Roepman R,Kremer H,Blacque OE
Wed Aug 20 00:00:00 EDT 2014
Acute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypes.
PLoS genetics
Hall EA,Keighren M,Ford MJ,Davey T,Jarman AP,Smith LB,Jackson IJ,Mill P
Wed Aug 20 00:00:00 EDT 2014
The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.
Nature cell biology
He M,Subramanian R,Bangs F,Omelchenko T,Liem KF,Kapoor TM,Anderson KV
Tue Jul 01 00:00:00 EDT 2014
Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma.
Proceedings of the National Academy of Sciences of the United States of America
Fu W,Asp P,Canter B,Dynlacht BD
Tue Jun 24 00:00:00 EDT 2014
Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma.
Proceedings of the National Academy of Sciences of the United States of America
Fu W,Asp P,Canter B,Dynlacht BD
Tue Jun 24 00:00:00 EDT 2014
Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes.
Nature communications
Wei Q,Xu Q,Zhang Y,Li Y,Zhang Q,Hu Z,Harris PC,Torres VE,Ling K,Hu J
Thu Jun 19 00:00:00 EDT 2014
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
The EMBO journal
Chaya T,Omori Y,Kuwahara R,Furukawa T
Mon Jun 02 00:00:00 EDT 2014
Detection of primary cilia in human glioblastoma.
Journal of neuro-oncology
Sarkisian MR,Siebzehnrubl D,Hoang-Minh L,Deleyrolle L,Silver DJ,Siebzehnrubl FA,Guadiana SM,Srivinasan G,Semple-Rowland S,Harrison JK,Steindler DA,Reynolds BA
Sat Mar 01 00:00:00 EST 2014
Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair.
PloS one
Dantas TJ,Daly OM,Conroy PC,Tomas M,Wang Y,Lalor P,Dockery P,Ferrando-May E,Morrison CG
Fri Feb 07 00:00:00 EST 2014
Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis.
Science (New York, N.Y.)
Das RM,Storey KG
Fri Jan 10 00:00:00 EST 2014
Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways.
American journal of physiology. Lung cellular and molecular physiology
Gilley SK,Stenbit AE,Pasek RC,Sas KM,Steele SL,Amria M,Bunni MA,Estell KP,Schwiebert LM,Flume P,Gooz M,Haycraft CJ,Yoder BK,Miller C,Pavlik JA,Turner GA,Sisson JH,Bell PD
Wed Jan 01 00:00:00 EST 2014
Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy.
American journal of human genetics
Schmidts M,Vodopiutz J,Christou-Savina S,Cortés CR,McInerney-Leo AM,Emes RD,Arts HH,Tüysüz B,D'Silva J,Leo PJ,Giles TC,Oud MM,Harris JA,Koopmans M,Marshall M,Elçioglu N,Kuechler A,Bockenhauer D,Moore AT,Wilson LC,Janecke AR,Hurles ME,Emmet W,Gardiner B,Streubel B,Dopita B,Zankl A,Kayserili H,Scambler PJ,Brown MA,Beales PL,Wicking C,Duncan EL,Mitchison HM
Thu Nov 07 00:00:00 EST 2013
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia.
Nature methods
Su S,Phua SC,DeRose R,Chiba S,Narita K,Kalugin PN,Katada T,Kontani K,Takeda S,Inoue T
Fri Nov 01 00:00:00 EDT 2013
Functional interaction between autophagy and ciliogenesis.
Nature
Pampliega O,Orhon I,Patel B,Sridhar S,Díaz-Carretero A,Beau I,Codogno P,Satir BH,Satir P,Cuervo AM
Thu Oct 10 00:00:00 EDT 2013
ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury.
Biochimica et biophysica acta
Wang S,Wei Q,Dong G,Dong Z
Tue Oct 01 00:00:00 EDT 2013
ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury.
Biochimica et biophysica acta
Wang S,Wei Q,Dong G,Dong Z
Tue Oct 01 00:00:00 EDT 2013
Subretinal gene therapy of mice with Bardet-Biedl syndrome type 1.
Investigative ophthalmology & visual science
Seo S,Mullins RF,Dumitrescu AV,Bhattarai S,Gratie D,Wang K,Stone EM,Sheffield V,Drack AV
Wed Sep 11 00:00:00 EDT 2013
Short-rib polydactyly and Jeune syndromes are caused by mutations in WDR60.
American journal of human genetics
McInerney-Leo AM,Schmidts M,Cortés CR,Leo PJ,Gener B,Courtney AD,Gardiner B,Harris JA,Lu Y,Marshall M,Scambler PJ,Beales PL,Brown MA,Zankl A,Mitchison HM,Duncan EL,Wicking C
Thu Sep 05 00:00:00 EDT 2013
CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.
EMBO reports
Yang Y,Roine N,Mäkelä TP
Thu Aug 01 00:00:00 EDT 2013
Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis.
Human molecular genetics
Barbelanne M,Song J,Ahmadzai M,Tsang WY
Sat Jun 15 00:00:00 EDT 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 EDT 2013
Exome sequencing identifies DYNC2H1 mutations as a common cause of asphyxiating thoracic dystrophy (Jeune syndrome) without major polydactyly, renal or retinal involvement.
Journal of medical genetics
Schmidts M,Arts HH,Bongers EM,Yap Z,Oud MM,Antony D,Duijkers L,Emes RD,Stalker J,Yntema JB,Plagnol V,Hoischen A,Gilissen C,Forsythe E,Lausch E,Veltman JA,Roeleveld N,Superti-Furga A,Kutkowska-Kazmierczak A,Kamsteeg EJ,Elçioğlu N,van Maarle MC,Graul-Neumann LM,Devriendt K,Smithson SF,Wellesley D,Verbeek NE,Hennekam RC,Kayserili H,Scambler PJ,Beales PL,Knoers NV,Roepman R,Mitchison HM
Wed May 01 00:00:00 EDT 2013
CCDC41 is required for ciliary vesicle docking to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Joo K,Kim CG,Lee MS,Moon HY,Lee SH,Kim MJ,Kweon HS,Park WY,Kim CH,Gleeson JG,Kim J
Tue Apr 09 00:00:00 EDT 2013
HDAC6 inhibition restores ciliary expression and decreases tumor growth.
Cancer research
Gradilone SA,Radtke BN,Bogert PS,Huang BQ,Gajdos GB,LaRusso NF
Mon Apr 01 00:00:00 EDT 2013
HDAC6 inhibition restores ciliary expression and decreases tumor growth.
Cancer research
Gradilone SA,Radtke BN,Bogert PS,Huang BQ,Gajdos GB,LaRusso NF
Mon Apr 01 00:00:00 EDT 2013
Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.
The Journal of cell biology
Jurisch-Yaksi N,Rose AJ,Lu H,Raemaekers T,Munck S,Baatsen P,Baert V,Vermeire W,Scales SJ,Verleyen D,Vandepoel R,Tylzanowski P,Yaksi E,de Ravel T,Yost HJ,Froyen G,Arrington CB,Annaert W
Mon Mar 18 00:00:00 EDT 2013
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
The EMBO journal
Kodani A,Salomé Sirerol-Piquer M,Seol A,Garcia-Verdugo JM,Reiter JF
Wed Feb 20 00:00:00 EST 2013
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
The EMBO journal
Kodani A,Salomé Sirerol-Piquer M,Seol A,Garcia-Verdugo JM,Reiter JF
Wed Feb 20 00:00:00 EST 2013
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Cell
Mukhopadhyay S,Wen X,Ratti N,Loktev A,Rangell L,Scales SJ,Jackson PK
Thu Jan 17 00:00:00 EST 2013
Centriole distal appendages promote membrane docking, leading to cilia initiation.
Genes & development
Tanos BE,Yang HJ,Soni R,Wang WJ,Macaluso FP,Asara JM,Tsou MF
Tue Jan 15 00:00:00 EST 2013
Superresolution STED microscopy reveals differential localization in primary cilia.
Cytoskeleton (Hoboken, N.J.)
Yang TT,Hampilos PJ,Nathwani B,Miller CH,Sutaria ND,Liao JC
Tue Jan 01 00:00:00 EST 2013
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
Cell
Goetz SC,Liem KF,Anderson KV
Fri Nov 09 00:00:00 EST 2012
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.
The Journal of cell biology
Liem KF,Ashe A,He M,Satir P,Moran J,Beier D,Wicking C,Anderson KV
Mon Jun 11 00:00:00 EDT 2012
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Human molecular genetics
Zhang Q,Seo S,Bugge K,Stone EM,Sheffield VC
Tue May 01 00:00:00 EDT 2012
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Human molecular genetics
Zhang Q,Seo S,Bugge K,Stone EM,Sheffield VC
Tue May 01 00:00:00 EDT 2012
Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein.
Nature
Firestone AJ,Weinger JS,Maldonado M,Barlan K,Langston LD,O'Donnell M,Gelfand VI,Kapoor TM,Chen JK
Sun Mar 18 00:00:00 EDT 2012
The role of RPGR in cilia formation and actin stability.
Human molecular genetics
Gakovic M,Shu X,Kasioulis I,Carpanini S,Moraga I,Wright AF
Thu Dec 15 00:00:00 EST 2011
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
PLoS genetics
Seo S,Zhang Q,Bugge K,Breslow DK,Searby CC,Nachury MV,Sheffield VC
Tue Nov 01 00:00:00 EDT 2011
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
PLoS genetics
Seo S,Zhang Q,Bugge K,Breslow DK,Searby CC,Nachury MV,Sheffield VC
Tue Nov 01 00:00:00 EDT 2011
Disruption of a ciliary B9 protein complex causes Meckel syndrome.
American journal of human genetics
Dowdle WE,Robinson JF,Kneist A,Sirerol-Piquer MS,Frints SG,Corbit KC,Zaghloul NA,Zaghloul NA,van Lijnschoten G,Mulders L,Verver DE,Zerres K,Reed RR,Attié-Bitach T,Johnson CA,García-Verdugo JM,Katsanis N,Bergmann C,Reiter JF
Fri Jul 15 00:00:00 EDT 2011
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Nature genetics
Garcia-Gonzalo FR,Corbit KC,Sirerol-Piquer MS,Ramaswami G,Otto EA,Noriega TR,Seol AD,Robinson JF,Bennett CL,Josifova DJ,García-Verdugo JM,Katsanis N,Hildebrandt F,Reiter JF
Sun Jul 03 00:00:00 EDT 2011
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.
Cell
Ezratty EJ,Stokes N,Chai S,Shah AS,Williams SE,Fuchs E
Fri Jun 24 00:00:00 EDT 2011
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.
Cell
Ezratty EJ,Stokes N,Chai S,Shah AS,Williams SE,Fuchs E
Fri Jun 24 00:00:00 EDT 2011
Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis.
Cell
Kobayashi T,Tsang WY,Li J,Lane W,Dynlacht BD
Fri Jun 10 00:00:00 EDT 2011
Complex interactions between genes controlling trafficking in primary cilia.
Nature genetics
Ocbina PJ,Eggenschwiler JT,Moskowitz I,Anderson KV
Wed Jun 01 00:00:00 EDT 2011
Functional characterization of putative cilia genes by high-content analysis.
Molecular biology of the cell
Lai CK,Gupta N,Wen X,Rangell L,Chih B,Peterson AS,Bazan JF,Li L,Scales SJ
Fri Apr 01 00:00:00 EDT 2011
Functional characterization of putative cilia genes by high-content analysis.
Molecular biology of the cell
Lai CK,Gupta N,Wen X,Rangell L,Chih B,Peterson AS,Bazan JF,Li L,Scales SJ
Fri Apr 01 00:00:00 EDT 2011
The cilia protein IFT88 is required for spindle orientation in mitosis.
Nature cell biology
Delaval B,Bright A,Lawson ND,Doxsey S
Fri Apr 01 00:00:00 EDT 2011
The cilia protein IFT88 is required for spindle orientation in mitosis.
Nature cell biology
Delaval B,Bright A,Lawson ND,Doxsey S
Fri Apr 01 00:00:00 EDT 2011
Primary cilia regulate mTORC1 activity and cell size through Lkb1.
Nature cell biology
Boehlke C,Kotsis F,Patel V,Braeg S,Voelker H,Bredt S,Beyer T,Janusch H,Hamann C,Gödel M,Müller K,Herbst M,Hornung M,Doerken M,Köttgen M,Nitschke R,Igarashi P,Walz G,Kuehn EW
Mon Nov 01 00:00:00 EDT 2010
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.
Genes & development
Mukhopadhyay S,Wen X,Chih B,Nelson CD,Lane WS,Scales SJ,Jackson PK
Fri Oct 01 00:00:00 EDT 2010
DISC1 regulates primary cilia that display specific dopamine receptors.
PloS one
Marley A,von Zastrow M
Fri May 28 00:00:00 EDT 2010
