Positive Control: HepG2, HepG2 conditioned medium
Predicted Reactivity: Rat (85%), Dog (96%), Pig (92%), Sheep (87%), Bovine (87%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
IGF2 encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C11orf43; FLJ22066; FLJ44734; IGF-II; IGF2; insulin-like growth factor 2 (somatomedin A); Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; insulin-like growth factor type 2; Multiplication-stimulating polypeptide; PP9974; Preptin; Somatomedin-A; T3M-11-derived growth factor
Gene Aliases: AL033362; C11orf43; GRDF; Igf-2; IGF-II; IGF2; M6pr; Mpr; Peg2; PP1446; PP9974