IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: B-actin zipcode-binding protein 1; coding region determinant binding protein; Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IMP-1; insulin-like growth factor 2 binding protein 1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; Insulin-like growth factor 2 mRNA-binding protein 1; insulin-like growth factor 2, binding protein 1; rZBP-1; VICKZ family member 1; VIon ChannelKZ1; ZBP-1; ZBP1; zipcode binding protein 1; Zipcode-binding protein 1; zipcode-binding protein-1
Gene Aliases: AL024068; AW549074; CRD-BP; CRDBP; D030026A21Rik; D11Moh40e; D11Moh45; IGF2BP1; IMP-1; IMP1; mir-3063; Neilsen; VICKZ1; ZBP-1; ZBP1
Molecular Function: RNA metabolism protein