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Proteintech
IGF2BP1 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-22803
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IGF2BP1 fusion protein Ag18859
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: YSNREQTRQ AIMKLNGHQL ENHALKVSYI PDEQIAQGPE NGRRGGFGSR GQPRQGSPVA AGAPAKQQQV DIPL
Target Information
IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-actin zipcode-binding protein 1; coding region determinant binding protein; Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IMP-1; insulin-like growth factor 2 binding protein 1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; Insulin-like growth factor 2 mRNA-binding protein 1; insulin-like growth factor 2, binding protein 1; KH-domain containing protein; rZBP-1; unnamed protein product; VICKZ family member 1; VIon ChannelKZ1; ZBP-1; ZBP1; zipcode binding protein 1; Zipcode-binding protein 1; zipcode-binding protein-1
Gene Aliases: AL024068; AW549074; CRD-BP; CRDBP; D030026A21Rik; D11Moh40e; D11Moh45; IGF2BP1; IMP-1; IMP1; mir-3063; Neilsen; VICKZ1; ZBP-1; ZBP1
UniProt ID: (Human) Q9NZI8, (Mouse) O88477, (Rat) Q8CGX0
Entrez Gene ID: (Human) 10642, (Mouse) 140486, (Rat) 303477
regulation of cytokine production
RNA localization
regulation of translation
nervous system development
positive regulation of cell proliferation
regulation of mRNA stability involved in response to stress
negative regulation of translation
pallium cell proliferation in forebrain
mRNA transport
CRD-mediated mRNA stabilization
neuronal stem cell population maintenance
dendrite arborization
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
positive regulation of cytoplasmic translation
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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