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IGFBP4 Polyclonal Antibody
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Product Details
BS-10585R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human IGFBP4, amino acids 181-254.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the insulin-like growth factor binding protein family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Band 3A; differentially expressed in B16F10 2; IBP-4; IGF-binding protein 4; IGFBP; IGFBP-4; Insulin like growth factor binding protein; Insulin-like growth factor-binding protein 4; unnamed protein product
Gene Aliases: AI875747; BP-4; Deb2; HT29-IGFBP; IBP4; IGF-BP4; IGFBP-4; IGFBP4
UniProt ID: (Human) P22692, (Mouse) P47879, (Rat) P21744
Entrez Gene ID: (Human) 3487, (Mouse) 16010, (Rat) 360622
MAPK cascade
regulation of cell growth
signal transduction
regulation of glucose metabolic process
regulation of growth
positive regulation of MAPK cascade
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of insulin-like growth factor receptor signaling pathway
type B pancreatic cell proliferation
negative regulation of canonical Wnt signaling pathway
inflammatory response
intracellular signal transduction
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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