Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ A
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: angiomodulin; IBP-7; IBP7; IGF-binding protein 7; IGFBP; IGFBP rP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin-like growth factor binding protein 7; Insulin-like growth factor-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; TAF; Tumor-derived adhesion factor
Gene Aliases: AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBP7; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
UniProt ID: (Human) Q16270
Entrez Gene ID: (Human) 3490
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