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          • Primary Antibodies ›
          • IGHMBP2 Antibodies

          Invitrogen

          IGHMBP2 Polyclonal Antibody

          View all (7) IGHMBP2 antibodies
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          Cite IGHMBP2 Polyclonal Antibody

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          • Antibody Testing Data (2)
          IGHMBP2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          IGHMBP2 Antibody (PA5-103794) in WB

          Western blot analysis of IGHMBP2 in mouse kidney. Samples were incubated with IGHMBP2 polyclonal antibody (Product # PA5-103794). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Product Details

          PA5-103794

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:3,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human IGHMBP2(Accession P38935), corresponding to amino acid residues G497-L517.
          View immunogen

          Conjugate

          Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          RRID

          AB_2853127

          Target Information

          5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AEP; antifreeze enhancer-binding protein; Antifreeze enhancer-binding protein ortholog; ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; Immunoglobulin mu-binding protein 2; immunoglobulin S mu binding protein 2; neuromuscular degeneration; p110 subunit; zinc finger, AN1-type domain 7

          View more View less

          Gene Aliases: AEP; CATF1; CMT2S; HCSA; HMN6; IGHMBP2; nmd; RIPE3b1; sma; SMARD1; Smbp-2; SMBP2; SMUBP2; ZFAND7

          View more View less

          UniProt ID: (Human) P38935, (Rat) Q9EQN5

          View more View less

          Entrez Gene ID: (Human) 3508, (Mouse) 20589, (Rat) 29532

          View more View less

          Molecular Function: DNA metabolism protein

          Function(s)
          DNA replication DNA repair DNA recombination transcription, DNA-templated regulation of transcription from RNA polymerase II promoter translation DNA duplex unwinding protein homooligomerization negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated transcription from RNA polymerase II promoter spinal cord motor neuron differentiation metabolic process
          Process(es)
          tRNA binding DNA binding DNA helicase activity single-stranded DNA binding RNA binding protein binding ATP binding DNA-dependent ATPase activity transcription factor binding RNA-dependent ATPase activity zinc ion binding ATP-dependent 5'-3' RNA helicase activity ribosome binding ATP-dependent 5'-3' DNA helicase activity nucleotide binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding nucleic acid binding helicase activity hydrolase activity metal ion binding protein self-association
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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