This target displays homology in the following species: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%
DNA-binding protein IKAROS functions in the specification and the maturation of the T lymphocyte. It also interacts with a critical control element in the terminal deoxynucleotidyl transferase promoter as well as with the promoters for other genes expressed during early stages of B-cell and T-cell development.
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Protein Aliases: 1 (Ikaros); CLL-associated antigen KW-6; DNA-binding protein Ikaros; hIk-1; Hs.54452; IKAROS; Ikaros (zinc finger protein); IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; KAROS family zinc finger 1 (Ikaros); LYF1; Lymphoid transcription factor LyF-1; PRO0758; protein phosphatase 1, regulatory subunit 92; subfamily 1A; zinc finger containing transcription factor; zinc finger protein; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1
Gene Aliases: 5832432G11Rik; BOS_3969; CVID13; hlk-1; Hs.54452; IK1; IKAROS; IKZF1; LyF-1; LYF1; mKIAA4227; PPP1R92; PRO0758; RGD1562979; Zfpn1a1; ZNFN1A1
UniProt ID: (Human) Q13422