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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 494 and 710 of Human IKBKE|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29294 targets IKBKE in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29294 immunogen is recombinant fragment corresponding to a region within amino acids 494 and 710 of Human IKBKE.
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IKK-i; IKK-related kinase epsilon; IKKE; IKKI; inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of nuclear factor kappa-B kinase subunit epsilon
IKBKE; IKK-E; IKK-i; IKKE; IKKI; KIAA0151