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Abnova
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Sequence of this protein is as follows: MDSRYLQLQL YLPSCSLLQG SGDSSLEKEF LGAPVGPSVS TPNSQHSSPS RSLSANSIKV EMYSDEESSR LLGPDERLLE KDDSVIVEDS LSEPLGYCDG SGPEPHSPGG IRLPNGKLKC DVCGMVCIGP NVLMVHKRSH TGERPFHCNQ CGASFTQKGN LLRHIKLHSG EKPFKCPFCN YACRRRDALT GHLRTHSVSS PTVGKPYKCN YCGRSYKQQS TLEEHKERCH NYLQSLSTEA QALAGQPGDE IRDLEMVPDS MLHSSSERPT FIDRLANSLT KRKRSTPQKF VGEKQMRFSL SDLPYDVNSG GYEKDVELVA HHSLEPGFGS SLAFVGAEHL RPLRLPPTNC ISELTPVISS VYTQMQPLPG RLELPGSREA GEGPEDLADG GPLLYRPRGP LTDPGASPSN GCQDSTDTES NHEDRVAGVV SLPQGPPPQP PPTIVVGRHS PAYAKEDPKP QEGLLRGTPG PSKEVLRVVG ESGEPVKAFK CEHCRILFLD HVMFTIHMGC HGFRDPFECN ICGYHSQDRY EFSSHIVRGE HKVG
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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